| 朱翔,周剑,朱文静,杨光伟,汪兰兰,邵丽洁,王卫东,康冬梅.不同糖耐量人群血清维生素D水平的变化[J].中国临床保健杂志,2016,(3):243-245. |
| 不同糖耐量人群血清维生素D水平的变化 |
| The changes of serum Vitamin D level in people with different glucose tolerance |
| 投稿时间：2016-03-25 |
| DOI：10.3969/J.issn.1672-6790.2016.03.006 |
| 中文关键词: 血糖 葡糖耐量试验 维生素D 葡萄糖代谢障碍 |
| 英文关键词: Blood glucose Glucose tolerance test Vitamin D Glucose metabolism disorders 〖FL |
| 基金项目:安徽省科技计划项目(12010402134) |
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| 中文摘要: |
| 目的 探讨血清维生素D在不同糖耐量状态下的变化。方法 根据血糖水平将79例受试者分为糖耐量正常组(NC组)、糖耐量减低组(IGT组)和2型糖尿病组(T2DM组),比较不同组间25羟维生素D3[25(OH)D3]水平及相关代谢指标的差异。结果 25(OH)D3在NC组、IGT组和T2DM组呈递减趋势,NC组、IGT组和T2DM组这三组间在餐后2h血糖、三酰甘油、低密度脂蛋白、体质量指数、稳态胰岛素评价指数(HOMA-IR)和25(OH)D3上差异有统计学意义。进一步行多元回归分析显示,25(OH)D3与HOMA-IR正相关,BMI与HOMA-IR负相关。结论 维生素D与糖代谢相关,可能参与了胰岛素抵抗。 |
| 英文摘要: |
| Objective To explore the level of serum Vitamin D with different degrees of impaired glucose tolerance.Methods according to the level of blood glucose,Seventy-nine patients were divided into normal glucose tolerance group(NC group),impaired glucose tolerance group(IGT group) and T2DM group according to the level of blood glucose 25- Hydroxyvitamins D(25(OH)D3) and related metabolic parameters were compared.Results The 25(OH)D3 has the digression trend in the NC group,IGT group and T2DM group.There were significant difference on p2hBG,TG,LDL,BMI,HOMA-IR and 25(OH)D3 among three groups.Multiple regression analysis indicates 25(OH)D3 was positively correlated with HOMA-IR and BMI was negatively correlated with HOMA-IR.Conclusion Vitamin D is related to glucose metabolism,and may contribute to insulin resistance. |
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