| 刘罗坤,冯雪萍,王颖,杨腾舜,欧翔.津力达颗粒联合二甲双胍对老年2型糖尿病患者血糖和血清炎性因子水平的影响[J].中国临床保健杂志,2017,20(1):71-73. |
| 津力达颗粒联合二甲双胍对老年2型糖尿病患者血糖和血清炎性因子水平的影响 |
| Influence of Jinlida particles combined metformin on blood glucose and serum inflammatory of elderly patients with type 2 diabetes |
| 投稿时间：2016-09-22 |
| DOI：10.3969/J.issn.1672-6790.2017.01.022 |
| 中文关键词: 糖尿病,2型 津力达颗粒 二甲双胍 血糖 肿瘤坏死因子α C反应蛋白质 白细胞介素6 |
| 英文关键词: Diabetes mellitus,type 2 Jinlida Metformin Blood glucose Tumor necrosis factor-alpha C-reactive protein Interleukin-6〖FL |
| 基金项目:浙江省医药卫生科技计划项目(2011KYB154) |
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| 中文摘要: |
| 目的 探讨津力达颗粒联合二甲双胍对老年2型糖尿病患者血糖、血清炎性因子水平的影响。方法 将120例老年2型糖尿病患者随机数字法分为2组,每组60例。对照组给予二甲双胍,观察组在对照组基础上加用津力达颗粒。治疗前后,对两组患者血糖指标包括空腹血糖(FPG)及餐后 2 h 血糖(2hPG)、血清肿瘤坏死因子α(TNF-α)、超敏C反应蛋白(hs-CRP)、白介素-6(IL-6)进行观察。结果 治疗后,两组的FPG、2hPG均显著下降,且观察组FPG、2hPG水平明显低于对照组(P<0.05)；治疗后,两组hs-CRP、IL-6、TNF-α水平显著降低,观察组hs-CRP、IL-6、TNF-α水平显著低于对照组(P>0.05)。结论 津力达颗粒联合二甲双胍对老年2型糖尿病患者血糖、血清炎性因子水平有改善作用。 |
| 英文摘要: |
| Objective To explore the influence of Jinlida particles combined metformin on blood glucose and serum inflammatory of elderly patients with type 2 diabetes.Methods One hundred and twenty cases of elderly patients with type 2 diabetes were randomly divided into two groups by random number method,60 cases in each group.Patients in the control group were given metformin and patients in observation group were given Jinlida particles combined metformin.Before and after treatment,the glycemic index [include fasting plasma glucose (FPG) and 2 h postprandial blood glucose (2hPG)] and serum factor [tumor necrosis factor-α (TNF-α),high-sensitivity C- reactive protein (hs-CRP),interleukin -6 (IL-6)] of two groups were observed.Results After treatment,the FPG,2hPG of two groups were significantly decreased,and FPG,2hPG of observation group were significantly lower than those of control group (P<0.05).After treatment,the hs-CRP,IL-6,TNF-α of two groups were significantly decreased and hs-CRP,IL-6,TNF-α of observation group were significantly lower than control group (P<0.05).Conclusion Jinlida particles combined metformin can effectively improve the glycemic index and serum inflammation of elderly patients with type 2 diabetes. |
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