| 汪星朦,孙兴怀,戴毅,温跃春,武立云.SAP10-2视野检测程序发现视野损害前青光眼黄斑区视功能损伤的能力[J].中国临床保健杂志,2018,21(6):748-751. |
| SAP10-2视野检测程序发现视野损害前青光眼黄斑区视功能损伤的能力 |
| 10-2SAP visual field test finds macular defects in preperimetric glaucoma patients |
| 投稿时间：2018-08-17 |
| DOI：10.3969/J.issn.1672-6790.2018.06.007 |
| 中文关键词: 青光眼,开角型 视野 诊断技术,眼科 |
| 英文关键词: Glaucoma,open-angle Visual fields Diagnostic techniques,ophthalmological 〖FL |
| 基金项目:国家自然科学基金(81430007)；上海市重中之重临床医学中心(2017ZZ01020) |
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| 中文摘要: |
| 目的 探究视野损害前青光眼(PPG)患者行SAP10-2是否比临床上通常采用的SAP24-2更敏感而利于青光眼的早期诊断。统计SAP10-2哪些区域和位点最易发生视野损伤,以期提示临床工作中哪一区域的诊断提示意义最高。方法 对符合纳入标准的36位视野损害前青光眼患者进行眼科基本检查和Humphrey 中心24-2和10-2阈值检测(SITA-Standard)。将SAP10-2模式偏差图分为6个区域,分别统计各区平均缺损值(aMD)和模式偏差图的68个位点中存在视野损害的位点。结果 纳入的36位视野损害前青光眼患者有21位(58%)的SAP10-2检查异常,说明SAP10-2比SAP24-2对极早期的视野损害的检出更敏感。SAP10-2异常的视野损害前患者视野损伤主要出现在上半侧[aMD=0.781±0.089(1/L),P=0.001]和上六分之一区域[aMD=0.680±0.167(1/L),P=0.002],并且3、7、9、13、18、20、21、22、27、29、33、41、53、56、59这15个位点为最易出现损伤的位点,绝大部分位于视野上方,鼻侧和颞侧分布较均匀。结论 SAP10-2每个点位间距更小,检查更精细,比SAP24-2对极早期青光眼视野损害的检出更敏感,且这类视野损伤多出现于上方,鼻侧颞侧无明显差别。 |
| 英文摘要: |
| To study whether 10-2 standard automatic perimetry (SAP) is more sensitive than 24-2SAP for detecting very early visual field (VF) defects in preperimetric glaucoma (PPG).To find the most common 10-2 SAP VF defect areas and test points,so as to determine the highest correlation sector for early diagnose of glaucoma. Methods 36 patients with preperimetric glaucoma meeting the inclusion criteria had a series of fundamental ophthalmology examinations,Humphrey Central 10-2 Threshold Test and Central 24-2 Threshold Test (SITA-Standard).Pattern deviation map of SAP10-2 were divided by 6 areas.The aMD value of every area were calculated,and every test point on the pattern deviation map underwent analysis to find the defected point. Results 21 of 36 PPG patients (58%) had abnormal 10-2SAP results.And the 10-2 SAP VF defects mostly lay in the superior hemisphere [aMD=0.718±0.089(1/L),P=0.001] and superior 1/6 sector[aMD=0.680±0.167(1/L),P=0.002].Fifty Points′ (no.3,7,9,3,18,0,21,2,27,9,33,1,53,6,59) MD values below zero of over 90% PPG paitents which SAP10-2 were abnormal,which mostly fell in the superior hemisphere,without significant difference of temporal and nasal areas. Conclusions 10-2 SAP is more sensitive than 24-2SAP for detecting very early VF defects in PPG.The superior hemisphere and superior 1/6 sector were mostly vulnerable,and there was no significant difference between temporal and nasal areas. |
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