| 陶慧婷,杨旭.耐碳青霉烯类肠杆菌科细菌耐药机制和危险因素研究进展[J].中国临床保健杂志,2018,21(6):849-853. |
| 耐碳青霉烯类肠杆菌科细菌耐药机制和危险因素研究进展 |
| Resistance mechanism and molecular epidemiology progress of carbapenem-resistant enterobacteriaceae |
| 投稿时间：2018-06-20 |
| DOI：10.3969/J.issn.1672-6790.2018.06.033 |
| 中文关键词: 抗药性,细菌 处方不当 肠杆菌科 分子流行病学 危险因素 |
| 英文关键词: Drug resistance,bacterial Inappropriate prescribing Enterobacteriaceae Molecular epidemiology Risk factors 〖FL |
| 基金项目: |
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| 中文摘要: |
| 随着抗生素的不合理使用,耐碳青霉烯类肠杆菌科细菌已成为公众健康的一大威胁,因其预后差,传播广泛而引起了全世界范围的关注和研究,且已经成为导致患者死亡的重要因素之一。我国的耐药菌感染率也在不断升高,以产碳青霉烯酶的耐碳青霉烯类肠杆菌科细菌(CRE)为主。在评估CRE感染的研究中,人们发现传播过程和预防感染同样重要。该文将从CRE的耐药机制,分子流行病学和危险因素等方面的研究进展进行阐述。 |
| 英文摘要: |
| With the inappropriate use of antibiotics,carbapenem-resistant Enterobacteriaceae bacteria (CRE) has become a serious public health threat.Due to its worldwide prevalence and poor prognosis,infection by CRE is one of the important causes of death,which has attracted worldwide attention and research.In our country,the infection rate of drug-resistant bacteria is also increasing,mainly based on CRE producing carbapenemase.In the research of assessing CRE infection,people found that the process of transmission is as important as the prevention strategies.In this review,we will expound the research progress of the resistance mechanism of CRE,molecular epidemiology and risk factors. |
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