文章摘要
刘春,殷子杰,曹志娜,等.中老年高血压病患者血同型半胱氨酸水平与颈动脉多普勒超声检测结果分析[J].中国临床保健杂志,2016,(3):249-251.
中老年高血压病患者血同型半胱氨酸水平与颈动脉多普勒超声检测结果分析
Analysis of serum homocysteine level and carotid doppler ultrasound in middle-aged patients with hypertension
投稿时间:2016-03-10  
DOI:10.3969/J.issn.1672-6790.2016.03.008
中文关键词: 高血压  半胱氨酸  超声检查,多普勒,彩色  颈动脉内膜中膜厚度
英文关键词: Hypertension  Cysteine  Ultrasonography,doppler,color  Carotid intima-media thickness 〖FL
基金项目:河南省教育厅项目(14A360001);河南中医学院博士科研基金项目(BSJJ2009-45,BSJJ2009-46)
作者单位E-mail
刘春 河南中医学院第三附属医院心内科,郑州 450008 liuchun-2006-tcm@163.com 
殷子杰 河南中医学院第三附属医院心内科,郑州 450008  
曹志娜 河南中医学院第三附属医院心内科,郑州 450008  
张志强 河南中医学院第三附属医院心内科,郑州 450008  
张志国 河南中医学院第三附属医院心内科,郑州 450008  
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中文摘要:
      目的 观察中老年原发性高血压患者血同型半胱氨酸(Hcy)水平与颈动脉超声检查结果的相关性。方法 将122例符合纳入标准的原发性高血压患者根据Hcy水平分为Hcy正常组、Hcy增高组,所有对象均检测Hcy,并进行颈动脉超声检测。结果 Hcy与颈动脉内膜中层厚度(CA IMT)呈正相关,与颈内动脉内径(ICA DIA)、颈内动脉收缩期血流速度(ICA SPV)、颈内动脉阻力指数(ICA RI)无明显相关性。随着Hcy水平增高,CA IMT明显增厚。结论 血Hcy水平增高与颈动脉内中膜增厚密切相关。说明其参与高血压动脉硬化,促进高血压大动脉的重构。
英文摘要:
      Objective To observe the correlation of serum homocysteine (Hcy) and ultrasound of carotid in middle- aged patients with hypertension. Methods One hundred and twenty two patients were enrolled and divided into the control group and hyperhomocysteinemia group according to the homocysteine. The Hey and ultrasound of carotid were detected in all subjects. Results The serum Hcy had no significant correlation to the ICA DIA, ICA SPV and ICA RI, but had close correlation to the CA IMT.The tendency of CA IMT increased with Hcy.Conclusions Hyperhomocysteinemia may be involved in the arteriosclerosis of hypertension and promote the remodeling of conducting arteries.
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