文章摘要
朱长琪,朱道明,高飞,孟令毅,豆正莉,胡承志,孙锟,徐俊,杨静,陆宗海.N-末端脑钠肽原用于急性心力衰竭诊断的价值评估[J].中国临床保健杂志,2016,(4):395-396.
N-末端脑钠肽原用于急性心力衰竭诊断的价值评估
Value of N-terminal brain natriuretic peptide in the diagnosis of accute heart failure
投稿时间:2016-02-27  
DOI:10.3969/J.issn.1672-6790.2016.04.020
中文关键词: 心力衰竭  利钠肽,脑  呼吸困难
英文关键词: Heart failure  Natriuretic peptide,brain  Dyspnea 〖FL
基金项目:
作者单位E-mail
朱长琪  changqizhu@163.com 
朱道明 安徽医科大学附属巢湖医院消化科,合肥 238000 daoming666@126.com 
高飞 安徽医科大学附属巢湖医院消化科,合肥 238000  
孟令毅   
豆正莉 安徽医科大学附属巢湖医院消化科,合肥 238000  
胡承志   
孙锟 安徽医科大学附属巢湖医院消化科,合肥 238000  
徐俊   
杨静 安徽合肥市第一人民医院急诊内科  
陆宗海 安徽医科大学附属巢湖医院消化科,合肥 238000  
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中文摘要:
      目的 探讨N-末端脑钠肽原对急性心力衰竭诊断的价值。方法 选择就诊的急性心力衰竭的患者106例,另选对照组52例,来源于同期因胸闷、气喘、呼吸困难就诊的患者,临床诊断排除急性心力衰竭,分别测定血浆N-末端脑钠肽原浓度,比较不同组患者的血浆N-末端脑钠肽原水平。结果 ≥75岁人群中,急性心力衰竭组N-末端脑钠肽原(88.41±14.72)pmol/L与对照组N-末端脑钠肽原(33.27±6.61)pmol/L比较,t=18.57,P<0.05。<75岁人群中,急性心力衰竭组N-末端脑钠肽原(32.73±5.97)pmol/L与对照组N-末端脑钠肽原(6.12±2.51)pmol/L比较,t=27.28,P<0.05。结论 急性心力衰竭患者N-末端脑钠肽原明显升高,N-末端脑钠肽原对急性心力衰竭诊断有意义。
英文摘要:
      Objective To explore the value of N-terminal brain natriuretic peptide in the diagnosis of acute heart failure.Methods A total of 158 patients with dyspnea were selected,including 106 patients with acute heart failure and 52 controls and 52 controls with other diease.The N-terminal brain natriuretic peptide were measured and compared.Results The N-terminal brain natriuretic peptide of acute heart failure[(88.41±14.72)pmol/L ]was significantly higher than that of the control group[(33.27±6.61)pmol/L] in people aged 75 years or older(t=18.57,P<0.05).The N-terminal brain natriuretic peptide of acute heart failure[(32.73±5.97)pmol/L]was significantly higher than that of the control group[(6.12±2.51)pmol/L](t=27.28,P<0.05).Conclusion The N-terminal brain natriuretic peptide is significantly increased in patients with acute heart failure,N-terminal brain natriuretic peptide detection has some diagnose value in patients with acute heart failure.
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