| 宋汝丹,程玲慧,李莹莹,等.左炔诺孕酮宫内节育系统预防子宫内膜异位症复发的临床疗效[J].中国临床保健杂志,2017,20(2):162-165. |
| 左炔诺孕酮宫内节育系统预防子宫内膜异位症复发的临床疗效 |
| The clinical efficacy of the levonorgestrel intrauterine system to prevent the recurrence of endometriosis |
| 投稿时间：2016-08-28 |
| DOI：10.3969/J.issn.1672-6790.2017.02.014 |
| 中文关键词: 子宫内膜异位症 左炔诺孕酮 宫内避孕器,含药 |
| 英文关键词: Endometriosis Levonorgestrel Intrauterine devices,medicated〖FL |
| 基金项目:安徽省年度科研计划基金项目( 10021303020) |
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| 中文摘要: |
| 目的 探讨左炔诺孕酮宫内节育系统(LNG-IUD)用于卵巢子宫内膜异位症保守性手术后的疗效、安全性以及复发情况。方法 选取72例进行卵巢子宫内膜异位症保守性手术的患者作为研究对象,其中36例于术后第1次月经来潮予以放置LNG-IUD,另36 例术后应用促性腺激素释放激素激动剂(GnRH-a)、中成药或未采取任何措施,于术后第3、6、12月观察其卵巢大小、卵巢功能、内膜厚度、糖类抗原125(CA125)、人附睾蛋白4(HE4)以及其痛经等情况的变化。结果 LNG-IUD可有效的预防卵巢子宫内膜异位囊肿腹腔镜保守性手术后的术后复发,同时可以缓解痛经、减少月经量、降低CA125水平,且对卵巢功能无影响。结论 LNG-IUD适用于预防卵巢子宫内膜异位症复发且患者依从性好。 |
| 英文摘要: |
| Objective To evaluate the efficacy,safety and recurrence of ovarian endometriosis by using levonorgestrel intrauterine system (LNG-IUD) after conservative surgery.Methods 72 women who has taken conservation surgery were selected as research subjects.36 cases were applied with LNG-IUD in their first postoperative menses after surgery.Among the other 36 cases,gonadotropin-releasing hormone agonist (GnGH-a),Chinese patent medicine or no intervening measure was adopted.The changes of the ovary size,ovary function,endometrial thickness,carbohydrate antigen 125 (CA125),human epididymis protein 4 (HE4) and dysmenorrhea situation were observed after 3,6 and 12 months.Results LNG-IUD effectively reduced the recurrence of ovarian endometriosis after laparoscopic conservative surgery.Moreover,it could relieve dysmenorrhea,reduce menstrual quantity and the level of CA125,and had no influence on ovarian function.Conclusion LNG-IUD is suitable for the prevention of recurrence of ovarian endometriosis with good compliance. |
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