文章摘要
郭子琰,关茹琦,吕晓琳,张伟,黄刚.老年轻度认知功能障碍与心输出量的关系[J].中国临床保健杂志,2017,20(4):411-413.
老年轻度认知功能障碍与心输出量的关系
Relationship between cardiac output and mild cognitive impairment in the elderly
投稿时间：2016-10-26  
DOI：10.3969/J.issn.1672-6790.2017.04.022
中文关键词: 轻度认知障碍  心排血量  危险因素  老年人
英文关键词: Mild cognitive impairment  Cardiac output  Risk factors  Aged〖FL
基金项目:石河子大学医学院第一附属医院资助项目(YL2015-S017)
作者单位E-mail
郭子琰 石河子大学医学院第一附属医院老年病科,石河子 832000 1194875905@qq.com 
关茹琦 石河子大学医学院第一附属医院老年病科,石河子 832000  
吕晓琳 石河子大学医学院第一附属医院老年病科,石河子 832000  
张伟 石河子大学医学院第一附属医院老年病科,石河子 832000  
黄刚 石河子大学医学院第一附属医院老年病科,石河子 832000  
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中文摘要:
      目的 探讨老年轻度认知障碍和心输出量的关系。方法 收集入选246例老年患者一般资料,行心脏彩色多普勒超声检查,用左心室射血分数(LVEF)和心输出量(CI)来评价心输出量,并应用蒙特利尔认知评估量表(MoCA)对研究对象进行认知功能评定,符合轻度认知障碍(MCI)诊断118例为病例组,余128例为对照组。结果 两组年龄、LVEF、CI差异有统计学意义(P1<0.01,P2<0.01,P3=0.045),病例组受教育程度与冠心病患者比例高于对照组,差异有统计学意义(16.1%比76.6%,P<0.01；74.6%比59.4%,P= 0.015)；LVEF与MoCA评分成正相关(r=0.157,P= 0.014)；多因素分析显示,与MCI有关的因素是年龄、受教育程度、LVEF、CI,其OR(95%CI)分别为1.126(1.065~1.191),0.068(0.034~0.138),0.935(0.894~0.978),0.724(0.528~0.993)。结论 心输出量减少是老年轻度认知功能障碍的独立危险因素。
英文摘要:
      Objective To explore the relationship between the cardiac output and mild cognitive impairment in the elderly.Methods The general information of selected 246 elderly patients was collected.The heart color doppler ultrasound examination was performed and left ventricular ejection fraction (LVEF) and cardiac output (CI) were examined to evaluate cardiac output.The application of Montreal Cognitive Assessment Scale (MoCA) in the study was for the assessment of cognitive function.118 cases with mild cognitive impairment (MCI) were include in the case group,and other 128 cases were in the control group.Results The age,CI and LVEF in the two groups were statistically different (P1<0.01,P2<0.01,P3=0.045).The level of education and proportion of the patients with coronary heart disease in the case group were higher than those in the control group,respectively,and the differences were statistically significant (16.1% VS.76.6%,P<0.01;74.6% VS.59.4%,P=0.01).LVEF was positively correlated with MoCA score (r=0.157,P=0.014).Multivariate analysis revealed that the factors associated with MCI were age,education,LVEF,CI and their OR (95%CI) were 1.126 (1.065-1.191),0.068 (0.034-0.138),0.935 (0.894-0.978) and 0.724 (0.528-0.993).Conclusion The decrease of cardiac output is an independent risk factor for mild cognitive impairment in the elderly.
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