| 苏静,顾朋颖.骨钙素与腹型肥胖关系的研究进展[J].中国临床保健杂志,2017,20(6):765-768. |
| 骨钙素与腹型肥胖关系的研究进展 |
| The research progress of the relationship between osteoealcin and abdominal obesity |
| 投稿时间：2016-10-26 |
| DOI：10.3969/J.issn.1672-6790.2017.06.040 |
| 中文关键词: 肥胖,腹部 骨钙素 危险因素 |
| 英文关键词: Obesity,abdominal Osteocalcin Risk factors 〖FL |
| 基金项目:安徽省卫生厅课题(13zc010) |
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| 中文摘要: |
| 骨钙素(OC)是一种由成骨细胞合成和分泌的非胶原蛋白。研究发现骨钙素不仅参与骨代谢过程,而且作为一种内分泌激素,参与机体的能量代谢,具有促进胰岛素分泌、增加胰岛素敏感性、改善胰岛B细胞功能及调节脂肪含量等作用,并与内脏脂肪含量相关,深入研究骨钙素的生物学作用将为肥胖以及心血管疾病的防治提供新思路。 |
| 英文摘要: |
| Osteocalcin (OC) is a non-collagen protein synthesized and secreted by osteoblasts.Now researches show that OC is involved in not only bone metabolism,but also plays a key role in the regulation of body energy metabolism as an endocrinal hormone.It could stimulate insulin secretion,enhance insulin sensitivity,improve islet β cell function,and regulates fat content,etc.An in-depth investigation on the biological functions of OC would inspire new strategies for prevention and treatment of obesity and cardiovascular diseases. |
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