文章摘要
史晓雪,唐世琪,徐丽娟,刘静,王瑾,刘化云.中老年男性动脉弹性与血清尿酸及血脂的相关性[J].中国临床保健杂志,2018,21(2):164-167.
中老年男性动脉弹性与血清尿酸及血脂的相关性
Correlation of arterial elasticity with the levels of serum uric acid and blood lipid in the middle-aged and elderly male population
投稿时间:2017-07-28  
DOI:10.3969/J.issn.1672-6790.2018.02.006
中文关键词: 动脉硬化  尿酸  血脂  危险因素
英文关键词: arteriosclerosis  uric acid  lipids  risk factors
基金项目:湖北省攻关计划项目(2015BKA335)
作者单位E-mail
史晓雪 武汉大学人民医院老年医学科,武汉 430060 1285621857@qq.com 
唐世琪 武汉大学人民医院老年医学科,武汉 430060 wh88063953@qq.com 
徐丽娟 武汉大学人民医院老年医学科,武汉 430060  
刘静 武汉大学人民医院老年医学科,武汉 430060  
王瑾 武汉大学人民医院体验中心,武汉 430060  
刘化云 武汉大学人民医院体验中心,武汉 430060  
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中文摘要:
      目的 研究中老年男性动脉弹性与血清尿酸及血脂水平的相关性。方法 选取男性体检者279例,进行体格、生化及动脉弹性检查,根据脉搏波传导速度(PWV)测定分为动脉硬化组138例,非动脉硬化组141例,分析动脉弹性与血清尿酸、血脂水平之间的相关性。结果 与非动脉硬化对照组比较,动脉硬化组血清尿酸[(409.38±92.78)mmol/L比(433.84±93.43)mmol/L]、三酰甘油(TG)[(1.64±0.83)mmol/L比(2.26±1.37)mmol/L]水平显著升高(P<0.05或 P<0.01),而低密度脂蛋白(LDL)、高密度脂蛋白(HDL)及总胆固醇(TCH)水平差异无统计学意义。Pearson相关性分析显示,年龄、腰围、TG与肱-踝脉搏波传导速度存在明显的正相关(r=0.169~0.439,P<0.05或 P<0.01)。结论 TG水平与动脉硬化密切相关,同时高尿酸血症、肥胖、高血压及血糖异常是中老年男性动脉硬化的危险因素。
英文摘要:
      Objective To study the correlation of arterial elasticity with the levels of serum uric acid and blood lipid in middle and elderly male population.Methods A total of 279 male were enrolledand physical,biochemical and arterial elasticity tests were performed.Based on the pulse wave velocity (PWV),these were divided into two groups including non-arteriosclerosis group of 138 cases and arteriosclerosis group of 141 cases.Then we analyzed the correlation of arterial elasticity with serum uric acid and blood lipid levels.Results Compared with the non-arteriosclerosis control group,the serum levels of UA [(409.38±92.78) mmol/L VS. (433.84±93.43) mmol/L] and TG [(1.64±0.83) mmol/L VS. (2.26±1.37) mmol/L] were significantly elevated in arteriosclerosis group (P<0.05 or P<0.01),while there was no significant difference on the levels of LDL,HDL and TCh between the two groups.Pearson correlation analysis showed that there was a positive correlation of PWV with age,waist circumference and TG (r=0.169-0.439,P<0.05 or P<0.01).Conclusion TG,hyperuricemia,obesity,hypertension and abnormal blood glucose are risk factors for atherosclerosis in middle-aged and elderly men.
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