| 陈衍秋,陈英俊.异丙托溴铵联合布地奈德混悬液雾化吸入治疗上呼吸道感染后慢性咳嗽的效果[J].中国临床保健杂志,2018,21(3):335-337. |
| 异丙托溴铵联合布地奈德混悬液雾化吸入治疗上呼吸道感染后慢性咳嗽的效果 |
| Clinical efficacy of ipratropium bromide combined with budesonide suspension inhalation in the treatment of chronic cough after upper respiratory tract infection |
| 投稿时间：2018-02-25 |
| DOI：10.3969/J.issn.1672-6790.2018.03.013 |
| 中文关键词: 呼吸道感染 咳嗽 异丙托溴铵 布地奈德 投药,吸入 |
| 英文关键词: Respiratory tract infections Cough Ipratropium bromide Budesonide Administration,inhalation〖FL |
| 基金项目:浙江省台州市科技计划项目(1301ky16) |
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| 中文摘要: |
| 目的 探讨异丙托溴铵联合布地奈德混悬液雾化吸入治疗上呼吸道感染后慢性咳嗽的临床效果。方法 选取上呼吸道感染后慢性咳嗽的患者110例,根据治疗方案不同分为2组,各55例。观察组采用异丙托溴铵联合布地奈德混悬液治疗,对照组给予氨溴索注射液治疗。比较两组治疗前后的临床疗效、呼气高峰流量(PEFR)和嗜酸粒细胞直接计数(EOS)、不良反应发生率、咳嗽症状评分以及症状消失时间。结果 治疗后,PEFR评分观察组[(81.23±4.57)分]高于对照组[(73.41±5.17)分],临床治疗总有效率观察组高于对照组(90.9%>67.3%)。EOS评分观察组[(132.54±14.21)分]低于对照组[(157.84±12.34)分],观察组症状消失时间以及咳嗽症状评分低于对照组(P<0.05)。两组药物不良反应发生率差异无统计学意义。结论 异丙托溴铵联合布地奈德混悬液治疗上呼吸道感染后慢性咳嗽的效果更显著。 |
| 英文摘要: |
| Objective To explore the clinical effect of inhalation of ipratropium bromide combined with budesonide suspension in the treatment of chronic cough after upper respiratory tract infection.Methods 110 patients with chronic cough after upper respiratory tract infection were selected and divided into 2 groups according to treatment methods,55 cases in each group.The observation group was treated with ipratropium bromide combined with budesonide suspension,and the control group was given ambroxol injection.The clinical efficacy,peak expiratory flow (PEFR),direct count (EOS),incidence of adverse reactions,cough symptom score and time of symptom disappearance between the two groups.Results After treatment,the PEFR score in observation group (81.23±4.57) was higher than that in the control group (73.41±5.17),and the total clinical treatment efficiency was higher than that of the control group (92%>69%).EOS score (132.54±14.21) was lower than that of the control group (157.84±12.34),and the symptom disappearance time and cough symptom score were lower than the control group (P<0.05).There was no significant difference in the incidence of adverse drug reactions between the two groups.Conclusion Ipratropium bromide combined with budesonide suspension is more effective in treating chronic cough after upper respiratory tract infection. |
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