文章摘要
陈晨,王夏芹,崔宁,彭俊夫,韩永生,褚俊.感染性心内膜炎130例临床分析[J].中国临床保健杂志,2018,21(3):402-404.
感染性心内膜炎130例临床分析
Clinical analysis on 130 cases with infective endocarditis
投稿时间:2017-09-17  
DOI:10.3969/J.issn.1672-6790.2018.03.029
中文关键词: 心内膜炎,细菌性  机会致病菌感染  抗药性
英文关键词: Endocarditis,bacterial  Opportunistic infections  Drug resistance 〖FL
基金项目:安徽省自然科学基金资助(1408085MH173)
作者单位E-mail
陈晨 安徽医科大学第四附属医院心血管内科,合肥230041 794518657@qq.com 
王夏芹 安徽医科大学第四附属医院心血管内科,合肥230041  
崔宁 安徽医科大学第四附属医院科研部,合肥230041  
彭俊夫 中国科学技术大学附属第一医院安徽省立医院 急诊内科  
韩永生 中国科学技术大学附属第一医院安徽省立医院 急诊内科  
褚俊 中国科学技术大学附属第一医院安徽省立医院心血管内科 13505516189@163.com 
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中文摘要:
      目的 分析感染性心内膜炎的临床特点、病原菌和耐药性。方法 收集近10年来130例感染性心内膜炎患者的临床资料,分析其临床特点、致病微生物、受累瓣膜,及院内及近期死亡率与内生肌酐清除率估计值的关系。结果 130例患者年龄(38.6±17.2)岁;分离菌株中链球菌(20.8%)、葡萄球菌(14.6%)最常见;以发热和心脏杂音为主要表现,并发心功能不全和脑梗死最多见;患者的死亡率和肾功能状况有明显相关性。结论 感染性心内膜炎致病菌株多样化、耐药菌增多,内生肌酐清除率的检测对IE的死亡率是一个很好的预测因子。
英文摘要:
      Objective To analyze the clinical characteristics,pathogenic bacteria and their resistances of infective endocarditis (IE).Methods One hundred and thirty cases of infective endocarditis were collected.The clinical features,pathogenic microorganism,involvement valves,and the relationship between in-hospital,recent mortality rates and glomerular filtration rate were analyzed retrospectively.Results The average age was(38.6±17.2) years old.Streptococcus and staphylococcus were the most common pathogenic bacteria.Main clinical manifestations included fever and heart murmur.and the cardiac dysfunction and cerebral infarction concomitant with infective endocarditis were the most common.There was a significant correlation between the mortality and endogenous creatinine clearnce rate.Conclusion The pathogenic microgranismsiu patient with IE are diversity and have increased resistance to antibasterial drug,endogenous creatinine clearance is a good predictor for the mortality rate of IE.
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