| 陈瑞莲,黄传兵,汪元,王桂珍,万磊,范海霞,葛瑶.中药保留灌肠治疗急性痛风性关节炎的临床疗效[J].中国临床保健杂志,2018,21(4):479-483. |
| 中药保留灌肠治疗急性痛风性关节炎的临床疗效 |
| The clinical curative effect in treating acute gouty arthritis by herb retention-enema |
| 投稿时间：2017-12-19 |
| DOI：10.3969/J.issn.1672-6790.2018.04.011 |
| 中文关键词: 关节炎,痛风性 灌肠 中草药 糖皮质激素类 消炎药,非甾类 |
| 英文关键词: Arthritis,gouty Enema Drugs,Chinese herbal Glucocorticoids Anti-inflammatory agents,non-steroidal 〖FL |
| 基金项目:国家临床重点专科风湿病科中医适宜技术临床应用开放基金项目(LCZDZKKFJJ008) |
|
| 摘要点击次数: 7130 |
| 全文下载次数: 4381 |
| 中文摘要: |
| 目的 观察中药保留灌肠方法治疗急性痛风性关节炎的临床疗效。方法 将60例急性痛风性关节炎患者按照随机数字表法分为治疗组、对照组,两组均给予基础治疗,对照组可应用非甾体抗炎药和(或)糖皮质激素,治疗组在上述方案基础上给予中药保留灌肠(院内制剂:黄苓解毒泄浊颗粒)。观察两组治疗前后中医证候、临床疗效及各项相关指标的变化。结果 治疗组在治愈率[12例(40%)比6例(20%),t=6.020,P=0.009]、显效率[12例(40%)比16例(53.3%),t =5.143,P=0.047]方面优于对照组；在降低患者中医证候总积分及关节疼痛视觉模糊评分评分方面优于对照组(P<0.01)；在改善关节局部症状(关节疼痛起效时间、关节肿胀起效时间)方面优于对照组(P<0.01)；在降低炎性指标(红细胞沉降率、C反应蛋白)及降低血尿酸方面均优于对照组(P<0.05,或P<0.01)。结论 中药保留灌肠治疗能显著改善痛风性关节炎急性发作症状,未见明显毒副作用,是治疗本病的有效方法之一。 |
| 英文摘要: |
| Objective To observe the clinical curative effect in treating acute gouty arthritis by herb retention-enema.Methods 60 patients with acute gouty arthritis were included in the study who were divided into the treatment group and the control group according to the random number table.Two groups were both given basic treatment,while the control group can use non-steroidal anti-inflammatory drug and (or) glucocorticoids,and the treating group used herb retention-enema (Hospital preparations:Huangling Jieduxiezhuo granule) on the basis of the above scheme.The clinical TCM syndrome,clinical effects examination and investigations were performed and disease activity was assessed.Results After treatment,patients in two groups both showed some trend of effectiveness.The treatment group was superior to the control group in the cure rate [12 patients (40%) vs 6 patients (20%),t=6.020,P=0.009] and the effective rate[12 patients(40%) vs 16 patients (53.3%),t=5.143,P=0.047],reducing the terms of TCM syndrome score and VAS score of joint pain (P<0.01),improving the the local symptoms of arthritis (pain onset time,swelling effect time) (P<0.01),reducing the inflammatory makers (ESR,CRP) and reducing serum uric acid (P<0.05 or P<0.01).Conclusion Herb retention-enema has effective control on the acute attack of gouty arthritis,without obvious toxic side effects when treating gout patients,thus can be used as one of effective therapeutic methods. |
|
查看全文
|
| 关闭 |
|
|
|