戴东方,张海峰.额颞叶痴呆[J].中国临床保健杂志,2018,21(5):700-704. |
额颞叶痴呆 |
Frontotemporal dementia |
投稿时间:2018-07-11 |
DOI:10.3969/J.issn.1672-6790.2018.05.035 |
中文关键词: 额颞叶变性 病理过程 体征和症状 诊断,鉴别 治疗 预后 |
英文关键词: Frontotemporal lobar degeneration Pathologic processes Signs and symptoms Diagnosis,differential Therapy Prognosis 〖FL |
基金项目:军队保健专项课题资助项目(14BJZ46) |
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中文摘要: |
额颞叶痴呆是一种与基因突变有关的因额叶和(或)颞叶的退行性变导致的一组临床综合征,以进行性精神行为异常、执行功能障碍、语言损害为主要表现,最终发展为全面的痴呆,同时可合并其他运动障碍,是常见的早老性痴呆,在临床表现、病理、遗传方面具有异质性,预后不佳。本文从该病的病因、临床表现、诊断、治疗、预后等多方面进行了介绍,以期提高对该病的认识。 |
英文摘要: |
Frontotemporal dementia is a group of clinical syndromes associated with gene mutation ,due to degenerative in the frontal temporal lobe,it manifested in the mental behavior abnormalities,executive dysfunction,language impairment and eventually developed into full-blown dementia,sometimes combined other sports disorders.It is a relatively common occurrence of dementia in the early years of old age and has heterogeneity in clincal manifestations,pathological changes and genetic factors.It has poor prognosis. |
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