| 谭清武,徐海涛,唐静怡,等.老年非糖尿病肺部感染患者空腹血糖作为多器官功能不全综合征诊断指标的评价研究[J].中国临床保健杂志,2019,22(3):319-321. |
| 老年非糖尿病肺部感染患者空腹血糖作为多器官功能不全综合征诊断指标的评价研究 |
| Evaluation study on the fasting blood glucose as a diagnostic indictor of MODSE caused by pulmonary infection in elderly patients with non diabetes |
| 投稿时间：2018-07-25 |
| DOI：10.3969/J.issn.1672-6790.2019.03.008 |
| 中文关键词: 呼吸道感染 多器官功能衰竭 肺炎 诊断技术和方法 血糖 老年人 |
| 英文关键词: Respiratory tract infections Multiple organ failure Pneumonia Diagnostic techniques and procedures blood glucose Aged 〖FL |
| 基金项目:河北省卫生计生委医学科学研究重点课题(ZD20140316) |
|
| 摘要点击次数: 5923 |
| 全文下载次数: 4614 |
| 中文摘要: |
| 目的 评价老年非糖尿病肺部感染患者的空腹血糖(FBG)作为肺部感染致老年多器官功能不全综合征(MODSE)诊断指标的临床价值。 方法 选择老年非糖尿病肺部感染患者(年龄≥65岁)作为研究对象。根据患者肺部感染期间的最高FBG值分为两组,FBG≥6.875 mmol/L者分入拟诊MODSE组,FBG＜6.875 mmol/L者分入拟诊非MODSE组,比较两组患者的MODSE发病情况。根据老年非糖尿病肺部感染患者的最高FBG及MODSE发病情况、绘制老年非糖尿病肺部感染患者最高FBG受试者工作特征(ROC)曲线,计算ROC曲线下面积及FBG≥6.875 mmol/L诊断肺部感染致MODSE的敏感度和特异度。 结果 共纳入168例老年非糖尿病肺部感染患者,均为男性,年龄范围78~103岁,年龄(89.10±4.04)岁；拟诊MODSE患者58例,拟诊非MODSE患者110例,拟诊MODSE组的MODSE发病率显著高于拟诊非MODSE组(86.2%比8.0%,χ2=101.466,P<0.001)。ROC曲线下面积为0.908,面积的95%可信区间为0.856~0.960(P＜0.001),FBG≥6.875 mmol/L诊断肺部感染致MODSE的敏感度为84.7%、特异度为92.7%。 结论 老年非糖尿病肺部感染患者FBG≥6.875 mmol/L可作为肺部感染致MODSE的诊断指标。 |
| 英文摘要: |
| Objective To evaluate the clinical value of fasting blood glucose (FBG) in elderly patients with non diabetic pulmonary infection as a diagnostic index of multiple organ dysfunction syndrome in the elderly (MODSE) caused by pulmonary infection. Methods Patients over 65 years old with non diabetic pulmonary infection were enrolled.According to the patient′s highest FBG level during pulmonary infection,all patients were divided in two groups.The cases whose highest FBG≥6.875 mmol/L were divided into suspicious MODSE group.The cases whose highest FBG<6.875 mmol/L were divided into suspicious non MODSE group.The onset of MODSE in suspicious MODSE group and suspicious non MODSE group were compared.The receiver operating characteristic curve (ROC) of the highest FBG level in elderly patients with non diabetic pulmonary infection was drawn.The clinical value of highest FBG in the diagnosis of MODSE caused by pulmonary infection in elderly patients with non diabetes were assessed. Results A total of 168 patients were enrolled in the analysis.All patients were male,aged 78-103 years old,average age (89.10±4.04).Among 168 patients,58 of them were patients with suspected MODSE,110 of them were patients with suspected non MODSE.The incidence of MODSE in suspicious MODSE group was significantly higher than that in suspicious non MODSE group (86.2% vs 8.0%,χ2=101.466,P<0.001).The area under the ROC curve was 0.908,and 95%CI was 0.856-0.960(P<0.001).When using FBG≥6.875 mmol/L diagnose MODSE induced by pulmonary infection in elderly patients with non diabetes,the sensitivity was 84.7% and the specificity was 92.7%. Conclusion FBG≥6.875 mmol/L can be used as a diagnostic indictor of MODSE induced by pulmonary infection in elderly patients with non diabetes. |
|
查看全文
|
| 关闭 |
|
|
|