| 陈积雄,黄晓燕,徐文星,等.糖化血红蛋白水平在老年2型糖尿病合并冠心病患者病情评估中的应用[J].中国临床保健杂志,2019,22(5):707-708. |
| 糖化血红蛋白水平在老年2型糖尿病合并冠心病患者病情评估中的应用 |
| Correlation between glycosylated hemoglobin level and coronary heart disease in elderly patients with type 2 diabetes mellitus |
| 投稿时间：2018-12-21 |
| DOI：10.3969/J.issn.1672-6790.2019.05.036 |
| 中文关键词: 糖尿病,2型 糖基化血红蛋白A 冠心病 老年人 |
| 英文关键词: Diabetes mellitus,type 2 Glycated hemoglobin A Coronary disease Aged 〖FL |
| 基金项目:海南省自然科学基金资助项目(817321) |
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| 中文摘要: |
| 目的 探讨糖化血红蛋白(HbA1c)水平在老年2型糖尿病(T2DM)患者中诊断冠心病的价值。方法 选择老年2型糖尿病患者198例,均行冠脉造影检查。其中合并冠心病患者101例、非冠心病患者97例。检测两组患者HbA1c水平,根据HbA1c水平,将合并冠心病患者分成A组,HbA1c<6.5% 。B组 7.5%≥HbA1c≥6.5%:C组 HbA1c>7.5%。统计冠脉病变支数及Gensini积分。结果 老年T2DM合并冠心病患者中的HbA1c水平较未合并冠心病者明显增高(P＜0.05),且随着HbA1c水平升高,冠状动脉狭窄越严重,两组Gensini积分差异有统计学意义(P＜0.05)。结论 对于老年2型糖尿病患者,HbA1c水平可在一定程度上判断患者冠状动脉狭窄程度。 |
| 英文摘要: |
| Objective To explore the value of glycosylated hemoglobin (HbA1c) level in the diagnosis of coronary heart disease in elderly patients with type 2 diabetes mellitus.Methods 198 elderly patients with type 2 diabetes mellitus were selected for coronary angiography,including 101 patients with coronary heart disease and 97 patients without coronary heart disease.HbA1c levels of patients in two groups were detected.According to HbA1c levels,patients with coronary heart disease were divided into group A with HbA1c<6.5%,group B with 7.5%≥HbA1c≥6.5% and group C with HbA1c>7.5%.And the number of coronary artery lesions and Gensini integral were calculated.Results The level of HbA1c in elderly patients with T2DM complicated with coronary heart disease was significantly higher than that of those without coronary heart disease,and the higher the level of HbA1c was,the more serious the coronary artery stenosis was,with statistically significant differences between two groups in Gensini integral.Conclusion HbA1c level is related to the stenosis degree of coronary artery in elderly patients with type 2 diabetes mellitus to some extent. |
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