| 刘林青,王娟,胡世莲,等.老年2型糖尿病患者合并骨质疏松的相关危险因素分析[J].中国临床保健杂志,2019,22(6):786-789. |
| 老年2型糖尿病患者合并骨质疏松的相关危险因素分析 |
| Evaluation of influencing factors in elder type 2 diabetic patients with osteoporosis |
| 投稿时间：2019-07-09 |
| DOI：10.3969/J.issn.1672-6790.2019.06.017 |
| 中文关键词: 糖尿病,2型 骨质疏松 危险因素 老年人 |
| 英文关键词: Diabetes mellitus-type 2 Osteoporosis Influencing factors Aged 〖FL |
| 基金项目:安徽省科技攻关项目(1501041142)；中央引导地方科技发展专项专业性技术创新平台项目(2017070503B041,YDZX20183400002555) |
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| 中文摘要: |
| 目的 分析老年2型糖尿病患者合并骨质疏松的相关危险因素。方法 收集124例年龄≥65岁的2型糖尿病患者病历资料。根据骨密度检测结果,分为骨质正常组和骨密度降低组(包括骨量减少组和骨质疏松组),其中骨质正常者40例,骨密度降低组84例。对这两组患者的性别、糖尿病病程、体质指数(BMI)、空腹血糖(FBG)、糖化血红蛋白(HbA1c)、血钙(Ca)、血磷(P)、血尿酸(UA)、总胆固醇(TC)、25-羟基维生素D[25-(OH)D3]指标进行比较分析。结果 老年2型糖尿病患者合并骨密度降低组的女性比例明显高于男性比例(P=0.022)。多因素logistic回归分析得出:糖尿病病程、BMI、HbA1c、P、25-(OH)D3均是老年2型糖尿病患者合并骨质疏松的独立危险因素(P<0.05)。结论 长糖尿病病程、低BMI、高HbA1c、高P、低25-(OH)D3是老年2型糖尿病患者合并骨质疏松的危险因素。 |
| 英文摘要: |
| Objective To analyze the risk factors of elderly patients with type 2 diabetes associated with osteoporosis.Methods A total of 124 patients with T2DM aged 65 years or older were enrolled.On the basis of bone mineral density data,the patients were divided into the normal bone mass group(n=40)and low bone mass group(osteopenia group and osteoporosis group (n=84).The gender,diabetes duration,body mass index (BMI),fasting blood glucose (FBG),hemoglobin A1c(HbA1c),serum calcium (Ca),blood phosphorus(P),blood uric acid(UA),total cholesterol (TC),and 25-hydroxyvitamin D[25-(OH)D3]among the two groups were compared and analyzed.Results The proportion low bone mass in female elderlly with T2DM was significantly higher than that of male group(P=0.022).The duration of diabetes,BMI,HbA1c,P,and 25-(OH)D3 were found as key risk factors of elderly patients with T2DM associated with osteoporosis after multivariate logistic regression analysis.Conclusion The duration of diabetes,low BMI,high HbA1c,high P,25-(OH)D3 are the risk factors of teoporosis in elderly patients with T2DM. |
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