| 仲彬,李杰,欣冰,等.原发性干燥综合征合并桥本甲状腺炎的临床特点[J].中国临床保健杂志,2020,23(2):213-215. |
| 原发性干燥综合征合并桥本甲状腺炎的临床特点 |
| Clinical analysis of primary sjogren's syndrome with Hashimoto thyroiditis |
| 投稿时间：2019-12-22 |
| DOI：10.3969/J.issn.1672-6790.2020.02.018 |
| 中文关键词: 干燥综合征 桥本病 自身抗体 甲状腺功能减退 脏器受累 |
| 英文关键词: Sjogren's syndrome Hashimoto disease Antibodies Typothyroidism Organ involvement 〖FL |
| 基金项目:江苏省南京市医学科技发展项目(YKK16256) |
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| 中文摘要: |
| 目的 分析原发性干燥综合征(pSS)合并桥本甲状腺炎(HT)的临床和实验室特点。方法 选取pSS患者118例,根据是否合并HT分为pSS合并HT组(32例)和pSS未合并HT组(86例),比较两组的临床症状和检验指标的差异。结果 118例pSS患者中27.1%合并HT,与未合并HT的pSS患者相比,合并HT的pSS患者口干、乏力症状的发生率增高(P＜0.05),红细胞沉降率(ESR)、免疫球蛋白G(IgG)增高(P＜0.05),类风湿因子(RF)阳性率增高(P＜0.05),甲状腺肿大和浆膜腔积液发生率增高(P＜0.05)。结论 pSS患者中HT发病明显增多,对口干、乏力明显、甲状腺肿大、IgG升高的患者,要及时测定甲状腺功能及抗体。 |
| 英文摘要: |
| Objective To analyze the clinical and laboratory characteristics of primary sjogren's syndrome (pSS) patients with Hashimoto thyroiditis.Methods A total of 118 pSS patients were selected and divided into pSS combined HT group (32 cases) and pSS non-HT group (86 cases) according to whether combined with HT.The clinical symptoms and laboratory results of the two groups were compared.Results Among 118 pSS patients,32 patients (27.1%) had HT.Compared with pSS patients without HT,the incidence of dry mouth and weakness were increased in pSS patients with HT(P<0.05),ESR and immunoglobulin G(IgG) were increased in pSS patients with HT(P<0.05),RF positive rate was increased in pSS patients with HT (P<0.05),and the incidence of goiter and serosal effusion were increased in pSS patients with HT(P<0.05).Conclusions The incidence of HT is significantly increased in pSS patients,and for patients with dry mouth,obvious weakness,goiter and increased IgG,thyroid function and antibodies should be timely measured. |
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