| 胡博,胡勇,徐生林,等.射频消融应用于四肢骨与软组织恶性肿瘤治疗的效果[J].中国临床保健杂志,2020,23(6):777-779. |
| 射频消融应用于四肢骨与软组织恶性肿瘤治疗的效果 |
| Effect of radiofrequency ablation in the treatment of malignant tumors of bone and soft tissue of extremities |
| 投稿时间：2020-08-22 |
| DOI：10.3969/J.issn.1672-6790.2020.06.013 |
| 中文关键词: 骨肿瘤 肿瘤,骨组织 射频消融术 预后 生活质量 |
| 英文关键词: Bone neoplasms Neoplasms,bone tissue Radiofrequency ablation Prognosis Quality of life 〖FL |
| 基金项目:安徽省自然科学基金项目(1808085QH245) |
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| 中文摘要: |
| 目的 探究射频消融在四肢骨与软组织恶性肿瘤治疗中的作用及对预后的影响。方法 选择我院2017年12月至2019年6月收治的82例四肢骨肿瘤患者,按随机数字表法分为观察组和对照组。观察组(42例)采用手术切除重建术合并射频消融治疗,对照组(40例)仅采用手术切除重建术,对比探讨射频消融在对肿瘤复发率、术中出血量、术后疼痛、功能恢复等方面的作用。结果 所有患者均获得6～18个月随访。观察组的手术时间[(121.07±16.69)min]比对照组[(102.21±18.24)min]长,但观察组术中出血量[(452.91±11.51)mL]较对照组[(610.27±13.70)mL]明显减少,差异有统计学意义(P＜0.05)；其中观察组复发率约为10.5%,低于对照组的20.0%,差异无统计学意义；术后1、3、6、12个月,两组VAS评分均较术前降低,且观察组术后1、3月的VAS评分均低于对照组,差异有统计学意义(P＜0.05)；肢体功能方面观察组的评分[(22.72±6.56)分]高于对照组的[(19.53±5.40)分],差异无统计学意义(P＞0.05)。结论 射频消融可以显著提升四肢骨肿瘤的临床疗效,提高患者生活质量。 |
| 英文摘要: |
| Objective To explore the role of radiofrequency ablation in the treatment ofmalignant tumorsof bone and soft tissue of the extremities and its impact on prognosis.Methods 82 patients with bone tumors of extremities admitted to our hospital from December 2017 to June 2019 were randomly divided into observation group and control group.42 patients in the observation group were treated with surgical excision and reconstruction combined with radiofrequency ablation,while 40 patients in the control group were only treated with surgical excision and reconstruction.The effects of radiofrequency ablation on tumor recurrence rate,intraoperative bleeding volume,postoperative pain and functional recovery were compared and discussed.Results All patients were followed up for 6-18 months.The operative time of the observation group[(121.07±16.69)min] was longer than that of the control group[(102.21±18.24)min],but the intraoperative blood loss[(452.91±11.51)mL] was significantly reduced compared with that of the control group[(610.27±13.70)mL],the difference was statistically significant(P＜0.05).The recurrence rate in the observation group was about 10.5%,which was lower than 20.0% in the control group,and the difference was not statistically significant.At 1,3,6 and 12 months after surgery,VAS scores in both groups were lower than those before surgery,and VAS scores in the observation group were lower than those in the control group at 1 and 3 months after surgery,with statistically significant differences(P＜0.05).The score of 22.72±6.56 in the observation group was higher than that of 19.53±5.40 in the control group,and the difference was not statistically significant(P＞0.05).Conclusion Radiofrequency ablation can significantly improve the clinical efficacy of limb bone tumors and improve the quality of life of patients. |
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