| 贺雪梅,储爱琴,王玉,等.肾移植受者术后感染的回顾性研究[J].中国临床保健杂志,2021,24(1):121-124. |
| 肾移植受者术后感染的回顾性研究 |
| Retrospective study of secondary infections among kidney transplant recipients |
| 投稿时间：2020-05-19 |
| DOI：10.3969/J.issn.1672-6790.2021.01.031 |
| 中文关键词: 肾移植 手术后并发症 回顾性研究 感染 |
| 英文关键词: Kidney transplantation Postoperative complications Retrospective studies Infections |
| 基金项目:国家临床重点专科建设项目(国卫办医函〔2018〕292号) |
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| 中文摘要: |
| 目的 探讨肾移植术后感染的发生率、病原菌谱及其危险因素。方法 回顾性研究2017年1月至2019年8月于某三级甲等医院成功进行肾移植手术的315例受者临床资料,分析其术后感染发生率、相关病原菌分布特点以及明确影响肾移植受者术后感染的相关因素。结果 共144例(45.71%)肾移植受者术后发生感染,且一年内高发(90例,62.50%)；病原菌检出共65株,以卡式肺孢子菌感染(14例,21.54%)多见；肺部(79例,54.48%)为主要感染部位。术后住院时间≥15 d是肾移植术后感染发生的危险因素(P＜0.001),术后预防性应用更昔洛韦或复方磺胺甲唑是其保护因素。结论 肾移植术后感染发生率较高,临床医务人员应采取针对性措施进行有效防治,改善患者预后。 |
| 英文摘要: |
| Objective To explore the incidence,pathogenic bacteria,related factors of secondary infections after kidney transplantation.Methods The clinical data of 315 recipients who underwent successful allograft kidney transplantation in a tertiary hospital from January 2017 to August 2019 were retrospectively analyzed,with a focus on the incidence of postoperative infection,distribution of related pathogens and the relevant factors affecting the postoperative infection of kidney transplant recipients.Results A total of 144(45.71%) kidney transplant recipients developed postoperative infections and had a high incidence within one year (90,62.50%).A total of 65 pathogenic bacteria were detected,more common with Pneumocystis carinii infection (14,21.54%).The lung (79,54.48%) was the main infection site.The length of hospital stay over 15 days was a risk factor for infection after kidney transplantation,and ganciclovir or SMZ was a protective factor after surgery.Conclusion The incidence of infection after kidney transplantation is very high,and clinical medical staff should take targeted measures to effectively improve the prognosis. |
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