| 郑昌志,燕雯雯,罗寅亮,等.维持性血液透析患者新发透析相关心房颤动的危险因素[J].中国临床保健杂志,2021,24(3):406-410. |
| 维持性血液透析患者新发透析相关心房颤动的危险因素 |
| Risk factors of new dialysis-related atrial fibrillation in patients with maintenance hemodialysis |
| 投稿时间：2020-10-17 |
| DOI：10.3969/J.issn.1672-6790.2021.03.028 |
| 中文关键词: 肾透析 心房颤动 危险因素 |
| 英文关键词: Renal dialysis Atrial fibrillation Risk factors 〖FL |
| 基金项目:国家自然科学基金青年项目(81403372) |
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| 中文摘要: |
| 目的 探讨维持性血液透析患者新发透析相关性心房颤动的风险因素。方法 采用回顾性队列研究的方法,选取2016年1月至2019年1月在我院接受维持性血液透析患者276例作为研究对象,收集患者临床资料,根据患者是否合并心房颤动分为心房颤动组和非心房颤动组,对比两组的临床指标,采用单因素和多因素logistic回归分析对维持性血液透析患者新发透析相关性心房颤动的风险因素探究,采用ROC曲线对危险因素预测维持性血液透析患者新发透析相关性心房颤动价值进行分析。结果 本次维持性血液透析患者中,透析相关性心房颤动发生率为11.59%。心房颤动组和非心房颤动组在年龄、心力衰竭、冠心病、室间隔厚度、透析血流量、C反应蛋白方面比较,差异有统计学意义(P＜0.05)。单因素logistic回归分析显示,年龄、心力衰竭、冠心病、右心房内径、左心房内径、室间隔厚度、透析血流量、C反应蛋白是维持性血液透析患者新发透析相关性心房颤动的因素(P＜0.05),多因素logistic回归分析结果显示,年龄、心力衰竭、室间隔厚度、C反应蛋白是维持性血液透析患者新发透析相关性心房颤动的危险因素,差异有统计学意义(P＜0.05)。ROC曲线显示室间隔厚度预测维持性血液透析患者发生心房颤动曲线下面积最大,为0.819,最佳临界值为12.20 mm时,敏感度为87.50%,特异度为51.79%。结论 年龄增加、出现心力衰竭、室间隔厚度增加、C反应蛋白升高是维持性血液透析患者新发透析相关性心房颤动的独立危险因素,其中室间隔厚度增加的预测价值最高。年龄、心力衰竭、室间隔厚度、C反应蛋白在预测维持性血液透析患者发生心房颤动具有一定价值,且室间隔厚度预测价值最高。 |
| 英文摘要: |
| Objective To explore the risk factors of new dialysis-related atrial fibrillation in patients with maintenance hemodialysis.Methods Two hundred and seventy six patients who underwent maintenance hemodialysis in our hospital from January 2016 to January 2019.The clinical data of the patients were collected,and they were divided into atrial fibrillation group and non-atrial fibrillation group according to whether the patients had atrial fibrillation,compared the clinical indicators of the two groups,using single-factor and multi-factor logistic regression analysis to explore the risk factors of new dialysis-associated atrial fibrillation in maintenance hemodialysis patients,The ROC curve was used to analyze the risk factors for predicting value of new dialysis-related atrial fibrillation in patients with maintenance hemodialysis.Results Among the patients undergoing maintenance hemodialysis,the incidence of dialysis-related atrial fibrillation was 11.59%.There was a statistically significant difference between the atrial fibrillation group and the non-atrial fibrillation group in age,heart failure,coronary heart disease,ventricular septal thickness,dialysis blood flow,and C-reactive protein (P＜0.05).Univariate logistic regression analysis showed that age,heart failure,coronary heart disease,right atrial diameter,left atrial diameter,ventricular septal thickness,dialysis blood flow,and C-reactive protein were factors for new dialysis-related atrial fibrillation in patients with maintenance hemodialysis (P＜0.05).Multivariate logistic regression analysis showed that age,heart failure,interventricular septal thickness,and C-reactive protein were risk factors for new dialysis-related atrial fibrillation in patients with maintenance hemodialysis.The differences were statistically significant (P＜0.05).The ROC curve showed that ventricular septal thickness predicts the largest area under the curve for atrial fibrillation in maintenance hemodialysis patients,0.819,the optimal cutoff value was 12.20mm,the sensitivity was 87.50%,and the specificity was 51.79%.Conclusions Age,heart failure,ventricular septal thickness,and C-reactive protein are risk factors for new dialysis-related atrial fibrillation in patients with maintenance hemodialysis.Age,heart failure,ventricular septal thickness,and C-reactive protein have certain value in predicting atrial fibrillation in patients with maintenance hemodialysis,The predicted value of interventricular septal thickness is the highest. |
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