| 黄益洲,余跃.老年人胃食管反流病治疗药物的选择[J].中国临床保健杂志,2022,25(2):161-164. |
| 老年人胃食管反流病治疗药物的选择 |
| Clinical choice of drugs for gastroesophageal reflux disease in the elderly |
| 投稿时间：2021-11-08 |
| DOI：10.3969/J.issn.1672-6790.2022.02.005 |
| 中文关键词: 胃食管反流 药物疗法 质子泵抑制剂 促胃肠动力药 老年人 |
| 英文关键词: Gastroesophageal reflux Drug therapy Proton pump inhibitors Prokinetic agents Aged 〖FL |
| 基金项目: |
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| 摘要点击次数: 1885 |
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| 中文摘要: |
| 胃食管反流病(GERD)是一种在老年人中普遍存在的疾病,常出现不典型症状,这增加了漏诊或误诊的可能性。与中青年患者相比,老年患者更容易出现严重的糜烂性食管炎和并发症,因此,选择合适药物会因为各种并发症和服用多种药物而变得更加复杂。质子泵抑制剂(PPI)是老年胃食管反流病患者短期和长期治疗的主要药物,而H2受体拮抗剂和促胃肠动力药也为治疗该病提供了更多选择。该文就老年GERD的药物治疗研究进展进行综述,以期为临床实践提供依据。 |
| 英文摘要: |
| Gastroesophageal reflux disease (GERD) is a common disease in the elderly,often with atypical symptoms,which increases the possibility of missed diagnosed or misdiagnosed.Compared with young and middle aged patients,elderly patients are more prone to severe erosive esophagitis and GERD complications.Therefore,due to various complications and taking multiple drugs,choosing the appropriate drug will become more complicated for elderly.Proton pump inhibitor (PPI) is the primary for short- and long-term treatment of elderly patients with GERD,while histamine-2 receptor antagonists (H2RAs) and prokinetic agents also provide more options for the treatment of the disease.This article reviews the research progress of the drug treatment of GERD in the elderly,and provides evidence for clinical practice. |
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