| 陈卫红,张磊,戴宁,等.老年人认知功能障碍和衰弱的相关性[J].中国临床保健杂志,2024,27(2):167-171. |
| 老年人认知功能障碍和衰弱的相关性 |
| Correlation between cognitive impairment and frailty in the elderly |
| 投稿时间：2024-04-02 |
| DOI：10.3969/J.issn.1672-6790.2024.02.006 |
| 中文关键词: 认知功能障碍 衰弱 慢性病共病 躯体功能 老年人 |
| 英文关键词: Cognitive dysfunction Frailty Multiple chronic conditions Physical functional performance Aged 〖FL |
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| 中文摘要: |
| 目的 探讨老年人认知功能障碍和衰弱的相关性。方法 回顾性分析2022年6月至2023年5月在北京市第六医院老年医学科住院的98例老年患者的综合评估数据,认知功能应用简易智能状态评定表评估,衰弱应用Fried衰弱表型和FRAIL量表分别进行评估。应用多因素logistic回归分析认知功能障碍与衰弱的关系。结果 98例患者中男性39例(39.8%),年龄(78.9±9.3)岁。基于Fried衰弱表型,无衰弱组、衰弱前期组和衰弱组认知功能障碍发生率分别为14.3%、17.2%和57.6%,组间差异有统计学意义(χ2=16.059,P<0.001)。基于FRAIL量表,无衰弱组、衰弱前期组和衰弱组认知功能障碍发生率分别为4.2%、25.0%和60.0%,组间差异有统计学意义(χ2=20.752,P<0.001)。有认知功能障碍组握力下降的发生率(70.0%)高于无认知功能障碍组(48.5%),差异有统计学意义(χ2=3.879,P=0.049)。有认知功能障碍组简易体能状况量表(SPPB)得分[(3.67±3.33)分]低于无认知功能障碍组[(6.75±2.97)分],差异有统计学意义(t=4.566,P<0.001)。行多因素logistic回归分析,将Fried衰弱表型评分作为自变量时(OR=4.253,95%CI:1.539~11.750,P=0.005)与将FRAIL量表评分作为自变量时(OR=4.052,95%CI:1.630~10.073,P=0.003)均提示认知功能障碍与衰弱密切相关。结论 老年人认知功能障碍与衰弱密切相关,老年人健康管理需要兼顾这两方面进行综合干预。 |
| 英文摘要: |
| Objective To explore the correlation between cognitive impairment and frailty in the elderly.Methods The data of comprehensive geriatric assessment in 98 elderly patients in Beijing NO.6 hospital from June 2022 to May 2023 was retrospectively analyzed.Cognitive impairment was assessed by MMSE.Frailty was evaluated by the Fried frailty phenotype and FRAIL scales respectively.Multivariate logistic regression was used to analyze the relationship between cognitive impairment and frailty.Results Among 98 patients,39 (39.8%) were male,and the age was (78.9±9.3) years old.Based on Fried frailty phenotype scale,the prevalence of cognitive impairment was 14.3% in the non-frailty patients,17.2% in the pre-frailty patients,and 57.6% in the frail patients,and the differences were statistically significant among the three groups (χ2=16.059,P<0.001).Based on FRAIL scale,the prevalence of cognitive impairment was 4.2% in the non-frailty patients,25.0% in the pre-frailty patients,and 60.0% in the frail patients,and the differences were statistically significant (χ2=20.752,P<0.001).The prevalence of grip strength decline in the subjects with cognitive impairment (70%) was higher than that in the subjects without cognitive impairment (48.5%),and the difference was statistically significant(χ2=3.879,P=0.049).The SPPB score of the group with cognitive impairment (3.67±3.33) was lower than that of the group without cognitive impairment (6.75±2.97),the difference was statistically significant(t=4.566,P<0.001).Multivariate logistic regression analysis was used,when Fried frailty phenotype was introduced as an independent variable (OR=4.253,95%CI:1.539-11.750,P=0.005),when FRAIL score was introduced as an independent variable (OR=4.052,95%CI:1.630-10.073,P=0.003),all indicated that cognitive impairment was closely related to frailty.Conclusions Cognitive impairment in the elderly is closely related to frailty,health management of the elderly needs to take into account the two aspects of comprehensive intervention. |
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