| 杨蕾,黎伟娟,胡学琴,等.个体化营养治疗对白族老年多器官功能障碍综合征患者炎症状态及生活质量的影响[J].中国临床保健杂志,2024,27(3):337-341. |
| 个体化营养治疗对白族老年多器官功能障碍综合征患者炎症状态及生活质量的影响 |
| Effects of individualized systematic nutrition support on the inflammation and quality of life of elderly patients with MODSE in Bai nationality |
| 投稿时间：2023-11-10 |
| DOI：10.3969/J.issn.1672-6790.2024.03.012 |
| 中文关键词: 多器官功能衰竭 营养状况 营养支持 炎症 生活质量 老年人 |
| 英文关键词: Multiple organ failure Nutritional status Nutritional support Inflammation Quality of life Aged 〖FL |
| 基金项目:云南省教育厅科学研究基金项目(2022J0742) |
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| 中文摘要: |
| 目的 探讨个体化营养治疗对白族老年多器官功能障碍综合征(MODSE)患者炎症状态及生活质量的影响。方法 选取2018年6月至2023年5月大理白族自治州人民医院收治的266例白族MODSE患者为研究对象,按照随机数字表法将患者分为2组,常规组133例予以全肠内营养治疗,系统营养组133例接受个体化系统营养治疗。观察2组患者营养状况、炎症状态以及生活质量。结果 干预14 d后,失访29例,最终共计纳入237例患者,其中系统营养组失访12例,常规组失访17例；干预7 d后,2组总蛋白(TP)、白蛋白(ALB)、血红蛋白(Hb)均较干预前下降,营养风险筛查2002(NRS2002)评分较干预前上升,但系统营养组TP、ALB、Hb高于常规组,NRS2002评分低于常规组(P<0.05)；干预14 d后,2组TP、ALB、Hb均较干预7 d后上升,NRS2002评分较干预7 d后下降,且系统营养组TP、ALB、Hb高于常规组,NRS2002评分低于常规组(P<0.05)；干预14 d后,2组C反应蛋白(CRP)、红细胞沉降率(ESR)以及白细胞介素(IL)-6水平均较干预前下降(P<0.05),且系统营养组CRP、ESR以及IL-6水平低于常规组(P<0.05)；干预14 d后,2组平均葡萄糖波动幅度、平均血糖标准差、最大葡萄糖波动幅度、平均血糖值较干预前下降(P<0.05),但系统营养组高于常规组(P<0.05)；干预7 d后以及干预14 d后,2组Bathel评分均较干预前上升且系统营养组高于常规组(P<0.05)。结论 个体化营养治疗白族MODSE患者,可改善营养状况,减轻炎症反应,促进生活质量的提高。 |
| 英文摘要: |
| Objective To explore the effect of individualized systematic nutritional support on the inflammatory status and quality of life of elderly patients with MODSE in Bai nationality.Methods Two hundred and sixty six cases of Bai MODSE patients admitted to People′s Hospital of Dali Bai Autonomous Prefecture Dali from June 2018 to May 2023 were prospectively selected as the research object,and all the patients were divided into two groups according to the random number table method.133 cases in the routine group received routine nutrition support intervention,and 133 cases in the systematic nutrition group received individualized systematic nutrition support intervention.The nutritional status,inflammatory status and quality of life of the two groups were observed.Results After the follow-up,29 cases were lost,and finally 237 patients were included,including 12 cases in the systematic nutrition group and 17 cases in the routine group.After 7 days of intervention,TP,ALB and Hb in both groups decreased and NRS2002 score increased,but TP,ALB and Hb in systematic nutrition group were higher than those in routine group,and NRS2002 score was lower than that in routine group (P<0.05).TP,ALB and Hb in both groups increased after 14 days of intervention,and NRS2002 score was higher than that after 7 days of intervention.After the intervention,the levels of CRP,ESR and IL-6 in the two groups decreased compared with those before the intervention (P<0.05),and the levels of CRP,ESR and IL-6 in the systematic nutrition group were lower than those in the routine group (P<0.05).After the intervention,MAGE,SDBG,LAGE and MBG in the two groups decreased (P<0.05),but the systematic nutrition group was higher than the routine group (P<0.05).After 7 days and 14 days of intervention,the Bathel scores of the two groups were higher than before intervention,and the systematic nutrition group was higher than the routine group (P<0.05).Conclusion Individualized systematic nutritional support can improve the nutritional status,reduce inflammatory reaction and improve the quality of life of Bai people with MODSE. |
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