| 姜晓亮,徐李滨,杨晓斌,等.环泊酚与丙泊酚应用于老年人无痛胃肠镜检查的效果比较[J].中国临床保健杂志,2024,27(4):529-532. |
| 环泊酚与丙泊酚应用于老年人无痛胃肠镜检查的效果比较 |
| Comparison of the application effect of cypropofol and propofol in elderly patients with painless gastroscopy examination |
| 投稿时间：2024-02-27 |
| DOI：10.3969/J.issn.1672-6790.2024.04.022 |
| 中文关键词: 内窥镜检查,胃肠道 麻醉 二异丙酚 血流动力学 疼痛,操作性 老年人 |
| 英文关键词: Endoscopy,gastrointestinal Anesthesia Propofol Hemodynamics Pain,procedural Aged 〖FL |
| 基金项目: |
| 作者 | 单位 | E-mail | | 姜晓亮 | 龙泉市人民医院,麻醉科,龙泉 323700 | 13884352478@163.com | | 徐李滨 | 龙泉市人民医院,消化内科,龙泉 323700 | | | 杨晓斌 | 龙泉市人民医院,麻醉科,龙泉 323700 | | | 毛卫波 | 龙泉市人民医院,麻醉科,龙泉 323700 | | | 廖张军 | 龙泉市人民医院,麻醉科,龙泉 323700 | | | 于红 | 龙泉市人民医院,麻醉科,龙泉 323700 | | | 江慧娟 | 龙泉市人民医院,麻醉科,龙泉 323700 | | | 周武强 | 龙泉市人民医院,麻醉科,龙泉 323700 | |
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| 中文摘要: |
| 目的 探讨环泊酚与丙泊酚在老年无痛胃肠镜检查中的应用效果。方法 回顾性分析2021年6月至2022年12月龙泉市人民医院收治的193例无痛胃肠镜检查老年人病历资料,根据所使用麻醉药品类型分为对照组(94例)和研究组(99例)。对照组给予丙泊酚乳状注射液进行麻醉,研究组给予环泊酚注射液进行麻醉。比较2组患者麻醉相关指标,入室后(T0)、麻醉诱导完成后(T1)、进镜后2 min(T2)、出室时(T3)的血压及不良反应发生情况。结果 研究组疼痛视觉模拟评分法(VAS)评分低于对照组(P<0.05)；2组麻醉诱导时间、插镜时间、胃镜检查时间、定向力恢复时间、苏醒时间、镇静成功率比较,差异无统计学意义(P>0.05)。研究组阿托品使用次数、阿托品用量、麻黄碱使用次数、麻黄碱用量与对照组比较,差异无统计学意义(P>0.05)。与T0比较,T1~T3时,2组舒张压(DBP)、收缩压(SBP)、平均动脉压(MAP)均呈逐渐降低趋势,且研究组T1~T3时的DBP、SBP、MAP均低于对照组(P<0.05)。观察期间,研究组疼痛、呼吸抑制发生率低于对照组(P<0.05)。结论 相比丙泊酚,环泊酚用于无痛胃肠镜检查时老年人血压稳定、疼痛减轻、呼吸抑制发病率低。 |
| 英文摘要: |
| Objective To explore the effects of cyclobenzaprine and propofol in painless gastroscopy examination in the elderly.Methods The clinical data of 193 elderly patients with painless gastroscopy examination in Longquan People′s Hospital from June 2021 to December 2022 were retrospectively collected,and they were divided into the control group (94 cases) and the experimental group (99 cases),the control group was anesthetized by giving propofol lactic injection and the experimental group was anesthetized by giving cypropofol injection.The anesthesia-related indexes,blood pressure and the occurrence of adverse reactions after entering the room (T0),after the completion of anesthesia induction (T1),2 min after entering the mirror (T2),and at the time of discharging from the room (T3) were compared between the two groups.Results The pain visual analog scale (VAS) score of the experimental group was lower than that of the control group (P<0.05);there was no difference in the anesthesia induction time,insertion time,gastroscopy time,orientation recovery time,awakening time,and sedation success rate between the two groups (P>0.05).There was no difference in the number of atropine use,atropine dosage,ephedrine use,ephedrine dosage in the experimental group compared with the control group (P>0.05).Compared with T0,diastolic blood pressure (DBP),systolic blood pressure (SBP),and mean arterial pressure (MAP) showed a trend of gradual decrease in both groups from T1 to T3,and DBP,SBP,and MAP were lower than those in the control group from T1 to T3 in the test group (P<0.05).During the observation period,the incidence of pain and suction inhibition in the experimental group were lower than the control group (P<0.05).Conclusion Compared to propofol,cyclosporine has stable blood pressure, reduced pain, and lower incidence of respiratory depression in elderly patients undergoing painless gastroscopy. |
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