| 马东宇,余晓凡,李周彤欣,等.原发性高血压患者冠状动脉周围脂肪衰减指数与左心室肥厚的相关性研究[J].中国临床保健杂志,2024,27(4):533-537. |
| 原发性高血压患者冠状动脉周围脂肪衰减指数与左心室肥厚的相关性研究 |
| Relationship between pericoronary fat attenuation index and left ventricular hypertrophy in patients with essential hypertension |
| 投稿时间：2024-04-11 |
| DOI：10.3969/J.issn.1672-6790.2024.04.023 |
| 中文关键词: 原发性高血压 肥大, 左心室 炎症 |
| 英文关键词: Essential hypertension Hypertrophy,left ventricular Inflammation 〖FL |
| 基金项目:国家自然科学基金项目(82370305)；苏州工业园区东方华夏心血管健康研究院一恒·心高血压/心肾保护医学研究基金项目(2022-CCA-HX-077) |
|
| 摘要点击次数: 678 |
| 全文下载次数: 1278 |
| 中文摘要: |
| 目的 探讨原发性高血压患者冠状动脉周围脂肪衰减指数(pFAI)与左心室肥厚(LVH)的关系。方法 回顾性分析2021年12月至2022年12月在安徽医科大学第一附属医院住院的原发性高血压患者61例。根据彩色多普勒超声心动图检查结果,按左心室质量指数(LVMI)分为高血压不伴LVH组(非LVH组,34例)和伴LVH组(LVH组,27例)。通过回顾患者的病历记录和冠状动脉CT血管成像(CCTA)影像资料,统计所有患者的一般临床资料、检验结果、心电图、超声心动图参数和CCTA数据及pFAI进行分析。结果 LVH组患者的冠状动脉左前降支(LAD)-脂肪衰减指数(FAI)[(-83.70±7.31)HU比(-88.29±7.00)HU,t=-2.483,P=0.016]、右冠状动脉(RCA)-FAI[(-82.78±10.41)HU比(-88.91±7.50)HU,t=-2.577,P=0.013]比非LVH组高,LVH组患者的冠状动脉回旋支(LCX)-FAI比非LVH组略高[(-82.15±6.48)HU比(-85.26±8.05)HU,t=-1.632,P=0.108]；与LVMI的偏相关分析显示LCX-FAI(r=0.435,P<0.001)、RCA-FAI(r=0.339,P=0.011)呈正相关,LAD-FAI(r=0.259,P=0.057)有相关趋势。结论 在原发性高血压患者中,pFAI与LVH呈正相关。 |
| 英文摘要: |
| Objective To investigate the relationship between pericoronary fat attenuation index (pFAI) and left ventricular hypertrophy (LVH) in patients with essential hypertension.Methods Sixty-one patients with essential hypertension hospitalized in the the First Affiliated Hospital of Anhui Medical University from December 2021 to December 2022 were included in this study.According to the left ventricular mass index (LVMI) by the color Doppler echocardiography results,the patients were divided into hypertension without LVH group (non-LVH group,n=34) and with LVH group (LVH group,n=27).The medical records and coronary computed tomography angiography (CCTA) imaging data were reviewed.And the general clinical information,laboratory results,electrocardiogram,echocardiography and CCTA data were collected and analyzed.Results Compared with the non-LVH group,patients in the LVH group showed an increase in LAD-FAI[(-83.70±7.31)Hu vs (-88.29±7.00)HU,t=-2.483,P=0.016]and RCA-FAI[(-82.78±10.41)HU vs (-88.91±7.50)HU,t=-2.577,P=0.013],with an ascending trend in LCX-FAI[(-82.15±6.48)HU vs (-85.26±8.05)HU,t=-1.632,P=0.108].There was positive correlation between pFAI with LVMI,specifically,LCX-FAI (r=0.435,P<0.001),RCA-FAI (r=0.339,P=0.011),and LAD-FAI (r=0.259,P=0.057).Conclusion pFAI is positively correlated with LVH in patients with essential hypertension. |
|
查看全文
|
| 关闭 |
|
|
|