| 袁芳,赵婵娜,郑丽梅,等.安徽省冠心病和缺血性脑卒中二级预防用药的现况调查[J].中国临床保健杂志,2024,27(5):626-630. |
| 安徽省冠心病和缺血性脑卒中二级预防用药的现况调查 |
| Status of secondary preventive drugs for coronary heart disease and ischemic stroke in Anhui province |
| 投稿时间：2024-07-28 |
| DOI：10.3969/J.issn.1672-6790.2024.05.012 |
| 中文关键词: 冠心病 卒中 二级预防 血小板聚集抑制剂 羟甲基戊二酰基CoA还原酶抑制剂 调查和问卷 |
| 英文关键词: Coronary disease Stroke Secondary prevention Platelet aggregation inhibitors Hydroxymethylglutaryl-CoA reductase inhibitors Surveys and questionnaires 〖FL |
| 基金项目:中央补助重大项目资金资助项目(皖财社〔2023〕26号,皖财社〔2023〕827号) |
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| 中文摘要: |
| 目的 调查安徽省冠心病和缺血性脑卒中患者二级预防用药情况,及与个体特征的相关关系。方法 问卷调查安徽省 15 个县/区的 145 543例 35~75岁的常住居民,自报冠心病和缺血性脑卒中患病情况和相关药物使用情况,并采用单变量因素和多变量混合效应模型分析其相关关系。结果 自报患有冠心病或缺血性脑卒中的有3 636例,患病率为2.49%。单因素回归分析显示,服用抗血小板药物或他汀类药物的患者中,男性、城市、非农民和高收入人群的药物使用率高于女性、农村、农民和低收入人群；超重和肥胖增加了服用二级药物风险,差异有统计学意义。多因素回归分析显示,女性(OR=0.69,95%CI:0.56~0.84,P<0.05)、农民(OR=0.39,95%CI:0.32~0.48,P<0.05)抗血小板药或他汀类药物的服用可能性低,而城市(OR=1.50,95%CI:1.24~1.81,P<0.05)、高中以上(OR=1.36,95%CI:1.05~1.77,P=0.021)和高血压患者(OR=1.56,95%CI:1.28~1.91,P<0.05)的药物使用可能性高。结论 安徽省冠心病和缺血性脑卒中患者二级预防药物使用率较低,可针对低靶点人群采取干预措施,增强心血管疾病人群二级预防的药物依从性。 |
| 英文摘要: |
| Objective To investigate the use of secondary preventive medication in patients with coronary heart disease and ischemic stroke in Anhui Province,and its correlation with individual characteristics.Methods There were 145 543 permanent residents aged 35-75 years old from 15 counties/districts in Anhui Province,who were selected and the coronary heart disease and ischemic stroke and related drug use were collected through a questionnaire survey.Univariable and multivariable mixed models were used to analyze the correlation.Results There were 3 636 patients(2.49%) with coronary heart disease or ischemic stroke among the participants.In univariable regression analysis,the drug use rate was higher in male,urban,non-agricultural and high-income groups than in female,rural,farmer and low-income groups among patients taking antiplatelet drugs or statins.Being overweight and obese increased the risk of secondary prevention therapies,and the difference was statistically significant.Multivariable regression analysis showed that women (OR=0.69,95%CI:0.56-0.84,P<0.05) and farmers (OR=0.39,95%CI:0.32-0.48,P<0.05) were less likely to take antiplatelet drugs or statins;cities (OR=1.50,95%CI:1.24-1.81,P<0.05),high school education or above (OR=1.36,95%CI:1.05-1.77,P=0.021) and hypertension (OR=1.56,95%CI:1.28-1.91,P<0.05) were more likely to use drugs.Conclusions The utilization rate of secondary preventive drugs in reported patients with coronary heart disease and ischemic stroke is lower in Anhui province,and targeted interventions can be taken to improve compliance with secondary preventive drug therapy in patients with cardiovascular diseases. |
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