| 王聪,王琴,郑凤鸣,等.腹部内脏脂肪厚度、尿酸、脂代谢变化及对老年人代谢综合征的预测价值[J].中国临床保健杂志,2025,28(1):120-124. |
| 腹部内脏脂肪厚度、尿酸、脂代谢变化及对老年人代谢综合征的预测价值 |
| Changes in visceral fat thickness,uric acid,and lipid metabolism in the abdomen and their predictive value for metabolic syndrome in elderly people |
| 投稿时间：2024-07-30 |
| DOI：10.3969/J.issn.1672-6790.2025.01.023 |
| 中文关键词: 代谢综合征 腹部脂肪 尿酸 脂代谢障碍 预测 老年人 |
| 英文关键词: Metabolic syndrome Abdominal fat Uric acid Lipid metabolism disorders Forecasting Aged 〖FL |
| 基金项目:浙江省杭州市科技局引导项目(20211231Y033) |
| 作者 | 单位 | E-mail | | 王聪 | 杭州市第三人民医院,老年医学二科,杭州 310000 | zjwcong@163.com | | 王琴 | 杭州市第三人民医院,老年医学一科,杭州 310000 | | | 郑凤鸣 | 杭州市第三人民医院,老年医学二科,杭州 310000 | | | 朱黎焱 | 杭州市第三人民医院,老年医学二科,杭州 310000 | | | 张方楹 | 杭州市第三人民医院,老年医学二科,杭州 310000 | | | 虞洁 | 杭州市第三人民医院,老年医学二科,杭州 310000 | | | 金厦 | 杭州市第三人民医院,老年医学二科,杭州 310000 | |
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| 中文摘要: |
| 目的 探究腹部内脏脂肪厚度、尿酸、脂代谢变化对老年人代谢综合征(MS)的预测价值。方法 回顾性分析2019年1月至2023年6月杭州市第三人民医院收治的160例老年人的临床资料。根据MS发生情况分为MS组(38例)及非MS组(122例),比较2组老年人腹部内脏脂肪厚度、尿酸、脂代谢指标；分析各指标对老年人出现MS的预测价值及MS患者各指标间的相关性；比较MS组及非MS组的临床资料,对老年人出现MS的影响因素进行分析。结果 MS组腹部内脏脂肪厚度大于非MS组,尿酸、总胆固醇(TC)、三酰甘油(TG)及低密度脂蛋白胆固醇(LDL-C)水平均高于非MS组(均P<0.05)。联合指标预测MS发生的曲线下面积(AUC)大于腹部内脏脂肪厚度、尿酸、脂代谢指标单独预测(P<0.05)。腹部内脏脂肪厚度与尿酸、TC、TG、LDL-C水平呈正相关,尿酸水平与TC水平呈正相关(P<0.05)。MS组患者年龄、体重指数(BMI)及收缩压、舒张压、空腹血糖值大于非MS组,腹部内脏脂肪厚度≥41.67 mm、尿酸≥329.74 μmol/L、TC≥5.85 mmol/L、TG≥2.46 mmol/L、LDL-C≥2.81 mmol/L及高密度脂蛋白胆固醇(HDL-C)<1.42 mmol/L的人数比例高于非MS组(P<0.05)。年龄较大、BMI值较大及腹部内脏脂肪厚度≥41.67 mm、尿酸≥329.74 μmol/L、TC≥5.85 mmol/L、TG≥2.46 mmol/L与MS发生风险升高有关(P<0.05)。结论 老年人群腹部内脏脂肪厚度增加、尿酸水平升高及脂代谢异常是老年人出现MS的危险因素。腹部内脏脂肪厚度、尿酸、脂代谢指标检测对MS发生具有预测价值,且联合检测对MS发生的预测价值高于单项检测。 |
| 英文摘要: |
| Objective To explore the changes of abdominal visceral fat thickness,uric acid and lipid metabolism in 160 elderly people and their predictive value on metabolic syndrome (MS).Methods The clinical data of 160 elderly patients admitted to Hangzhou Third People′s Hospital from January 2019 to June 2023 was analyzed.They were divided into MS group and non-MS group.The abdominal visceral fat thickness,uric acid and lipid metabolism indicators were compared between the two groups.The predictive value of each indicator on MS in elderly people was analyzed,and the correlation among the various indicators was analyzed.The clinical data were compared between MS group and non-MS group,and the influencing factors of MS in elderly people were analyzed.Results The thickness of abdominal visceral fat in MS group was thicker than that in non-MS group,and the levels of uric acid,total cholesterol (TC),triglyceride (TG) and low-density lipoprotein cholesterol (LDL-C) were higher than those in non-MS group (P<0.05).The area under curve (AUC) of combined detection in predicting the occurrence of MS was greater than that of abdominal visceral fat thickness,uric acid or lipid metabolism alone(P<0.05).Abdominal visceral fat thickness was positively correlated with uric acid,TC,TG and LDL-C levels,and uric acid level was positively correlated with TC level(P<0.05).The age,BMI,systolic blood pressure,diastolic blood pressure and fasting blood glucose in MS group were higher than those in non-MS group,and the proportions of people with abdominal visceral fat thickness ≥41.67 mm,uric acid ≥329.74 μmol/L,TC≥5.85 mmol/L,TG ≥2.46 mmol/L,LDL-C ≥2.81 mmol/L and high-density lipoprotein cholesterol(HDL-C) <1.42 mmol/L were higher than those in non-MS group(P<0.05).Older age,higher BMI,abdominal visceral fat thickness ≥41.67 mm,uric acid ≥329.74 μmol/L,TC≥5.85 mmol/L and TG≥2.46 mmol/L were associated with an increased risk of MS(P<0.05).Conclusions Increased visceral fat thickness,elevated uric acid levels,and abnormal lipid metabolism in the elderly are risk factors for developing MS.The detection of visceral fat thickness,uric acid,and lipid metabolism indicators in the abdomen has predictive value for the occurrence of MS,and the predictive value of combined detection is higher than that of single detection for MS. |
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