| 梁碧娟,顾俊,苏建培,等.老年慢性心力衰竭合并衰弱患者发生肌少症的影响因素分析[J].中国临床保健杂志,2025,28(2):196-199. |
| 老年慢性心力衰竭合并衰弱患者发生肌少症的影响因素分析 |
| The influence factors of sarcopenia in elderly patients with chronic heart failure complicated with weakness |
| 投稿时间：2024-08-11 |
| DOI：10.3969/J.issn.1672-6790.2025.02.009 |
| 中文关键词: 肌减少症 衰弱 心力衰竭 危险因素 老年人 |
| 英文关键词: Sarcopenia Frailty Heart failure Risk factors Aged 〖FL |
| 基金项目:云南省昆明市科技计划项目(2024-1-NS-029)；云南省昆明市卫生科技人才培养项目 [2022-SW(后备)-46] |
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| 中文摘要: |
| 目的 探讨住院老年慢性心力衰竭(CHF)合并衰弱患者发生肌少症的影响因素。方法 采用前瞻性研究,纳入213例老年CHF患者,用东华原DBA-210人体成分分析仪完成入选患者四肢肌肉指数(ASMI)测定,结合6 m步行试验(步速)、握力测定,筛选出其中合并肌少症的患者。同时根据FRAIL量表对入组患者进行衰弱筛查,比较肌少症组与非肌少症的衰弱发生率、ASMI、步速、握力、B型利钠肽前体(NT-proBNP)、白蛋白水平。并对住院老年CHF患者发生肌少症的相关危险因素进行分析。结果 老年CHF合并衰弱时,肌少症发生率高于非合并衰弱者(65.00%与20.26%,P＜0.001)；肌少症组与非肌少症组比较,在年龄、ASMI、步速、握力、NT-proBNP、白蛋白水平等比较,差异有统计学意义(P＜0.05)。多因素logistic回归分析提示,老年CHF患者,年龄是发生肌少症的危险因素,高ASMI、步速快、高握力、高白蛋白是老年CHF患者发生肌少症的保护因素。结论 老年CHF患者特别是高龄、合并衰弱、营养不良、运动能力低下的患者,需要及时筛查肌少症危险因素并进行早期干预。 |
| 英文摘要: |
| Objective To explore the influence factors of sarcopenia in hospitalized elderly patients with chronic heart failure(CHF).Methods Two hundred and thirteen elderly patients with CHF who met the inclusion criteria of the study were collected.The limb muscle index(ASMI) of the enrolled patients was determined using Donghuayuan DBA-210 body composition analyzer.The patients with sarcopenia were selected by 6 m walking test(walking speed) and grip strength measurement.At the same time,FRAIL screening was performed on the enrolled patients according to the frail scale,and the frailty incidence,ASMI,walking speed,grip strength,B-type natriuretic peptide precursor(NT-proBNP) and albumin level of the sarcopenia group and the non-sarcopenia group were compared.The risk factors of sarcopenia in hospitalized elderly patients with CHF were analyzed.Results When CHF was combined with frailty in the elderly,the incidence of sarcopenia was significantly higher than that without frailty(65.00% vs 20.26%,P＜0.001).There were significant differences in age,muscle index(ASMI),walking speed,grip strength,NT-proBNP and serum albumin level between sarcopenia group and non-sarcopenia group(P<0.05).Multivariate logistic regression analysis showed that age was a risk factor for the occurrence of sarcopenia in elderly patients with CHF,and high ASMI,fast walking speed,high grip strength and high albumin were protective factors for sarcopenia in elderly CHF patients.Conclusions Among elderly patients with heart failure,especially those with advancedage,frail,malnourished,and low mobility,it is important to screen for risk factors for sarcopenia in a timely manner and conduct early intervention. |
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