| 陈光,王靖怡,高嘉良.补肾活血抗衰老治疗心血管疾病的理论探讨与临床研究进展[J].中国临床保健杂志,2025,28(2):284-288. |
| 补肾活血抗衰老治疗心血管疾病的理论探讨与临床研究进展 |
| Review on theoretical discussion and clinical study of kidney-replenishing and blood-activating anti-aging treatment for cardiovascular diseases |
| 投稿时间：2025-01-20 |
| DOI：10.3969/J.issn.1672-6790.2025.02.027 |
| 中文关键词: 心血管疾病 抗衰老药(中药) 肾虚血瘀 补肾 活血 综述 |
| 英文关键词: Cardiovascular diseases Antiaging agents |
| 基金项目:中央高水平中医医院临床研究和成果转化能力提升项目(HLCMHPP2023008)；国家中医药管理局中医药传承与创新“百千万”人才工程(岐黄工程)项目(2018) |
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| 中文摘要: |
| 人口老龄化已成为我国重要的公共卫生与医学问题。抗衰老领域的研究在过去的30年取得了较多进展。中医药抗衰老虽然历史悠久,但各家观点不一。该文系统梳理中医传统理论,并总结现代科学研究成果提出:肾虚血瘀是中医对衰老的核心认识,而补肾活血是中医抗衰老的重要治法。其中,补肾活血方作为补肾活血治法的代表可用于心血管疾病的治疗实践。具有活血功效的中药三七提取物三七总皂苷以及丹参提取物丹参酮类可通过抗衰老途径干预动脉粥样硬化的病理环节,而具有补肾功效的中药灵芝、何首乌、枸杞等中药中包含的活性成分单体亦可以通过抑制慢性炎症、调节脂质代谢、降低氧化损伤等抗衰老的分子途径控制心血管疾病的进展。 |
| 英文摘要: |
| Population aging has become an important public health and medical issue in our country.Research in the field of anti-aging has made significant progress over the past 30 years.Although traditional Chinese medicine (TCM) has a long history in anti-aging,opinions vary among different schools of thought.This article systematically reviews traditional TCM theories and summarizes modern scientific research findings,proposing that kidney deficiency and blood stasis are core concepts of aging in TCM,and that replenishing the kidneys and activating blood is an important treatment method for anti-aging in TCM.Among these,the Kidney-Replenishing and Blood-Activating Formula serves as a representative treatment for cardiovascular disease.Herbal extracts such as Panax notoginseng saponins and salvianolic acid can also treat cardiovascular diseases through anti-aging pathways.Active compounds found in herbs like Reishi,He Shou Wu,Ginseng,Astragalus,and Goji Berries have also been shown to intervene in cardiovascular diseases through various aging pathways.The theory and formulas for replenishing the kidneys and activating blood proposed in this article can guide the clinical practice of TCM in anti-aging. |
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