| 孙雪莲,董碧蓉.老年认知-运动双维损害:运动认知风险综合征和生理认知衰退综合征[J].中国临床保健杂志,2025,28(5):600-604. |
| 老年认知-运动双维损害:运动认知风险综合征和生理认知衰退综合征 |
| Dual-dimensional cognitive-motor impairment in the old adults:motor cognitive risk syndrome and physiological cognitive decline syndrome |
| 投稿时间：2025-08-12 |
| DOI：10.3969/J.issn.1672-6790.2025.05.003 |
| 中文关键词: 运动认知风险综合征 生理认知衰退综合征 步行速度 手部肌力 认知功能障碍 |
| 英文关键词: Motoric cognitive risk syndrome Physio-cognitive decline syndrome Walking speed Hand strength Cognitive dysfunction 〖FL |
| 基金项目:国家自然科学基金重大研究计划项目(92248304)；中国博士后科学基金资助项目(GZC20241144)；国家老年疾病临床医学研究中心(华西医院)1·3·5学科发展工程项目(Z2024YY002) |
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| 中文摘要: |
| 运动认知风险综合征(MCR)和生理认知衰退综合征(PCDS)是近年来提出的2种新型老年综合征,在痴呆早期识别中发挥重要作用。MCR以步速减慢和主观认知下降为特征,PCDS则表现为步速和(或)握力下降伴客观认知障碍。2种综合征的识别有助于扩大痴呆高危人群的筛查范围且这2种综合征均具有一定的可逆性,为早期干预提供了重要机会。近年来,中国学者在MCR风险预测模型构建、分层健康管理等方面取得重要进展。本文系统梳理了MCR和PCDS的定义标准、流行病学特征、发病机制、危险因素及临床意义,并探讨了相应的健康管理策略,为老年痴呆的早期防控提供新思路。 |
| 英文摘要: |
| Motor cognitive risk syndrome (MCR) and physiological cognitive decline syndrome (PCDS) are two novel geriatric syndromes proposed in recent years,playing a significant role in the early identification of dementia.MCR is characterized by a slowed gait speed and subjective cognitive decline,while PCDS is manifested by a decreased gait speed and/or grip strength accompanied by objective cognitive impairment.Both syndromes have a certain degree of reversibility,providing important opportunities for early intervention.In recent years,Chinese scholars have made significant progress in the construction of MCR risk prediction models and stratified health management.The identification of these two syndromes helps to expand the screening scope of high-risk groups for dementia.This article systematically reviews the definition standards,epidemiological characteristics,pathogenesis,risk factors,and clinical significance of MCR and PCDS,and explores corresponding health management strategies,providing new ideas for the early prevention and control of dementia in the elderly. |
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