文章摘要
杨雪妍,王国宏.老年直立性低血压合并心功能不全的研究进展[J].中国临床保健杂志,2025,28(6):736-740.
老年直立性低血压合并心功能不全的研究进展
Research progress on orthostatic hypotension in the elderly with cardiac insufficiency
投稿时间:2025-07-15  
DOI:10.3969/J.issn.1672-6790.2025.06.003
中文关键词: 低血压,直立性  心脏病  老年人  综述
英文关键词: Hypotension,orthostatic  Heart diseases  Aged  Review 〖FL
基金项目:
作者单位E-mail
杨雪妍 首都医科大学附属北京同仁医院老年医学科,北京 100176 429326154@qq.com 
王国宏 首都医科大学附属北京同仁医院老年医学科,北京 100176  
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中文摘要:
      直立性低血压在老年人群中发病率较高,主要的发病机制为压力感受器反射敏感性下降、自主神经调节功能障碍以及血流动力学异常引起血压调节障碍,是导致心脑血管事件包括急性冠状动脉事件、心力衰竭、卒中的重要危险因素。老年人心功能不全合并直立性低血压的患病率高,且预后较差。近年来,这类患者逐渐受到临床重视,但两者之间的相互作用机制仍未阐明,对于此类患者的综合管理方案仍不规范。本文旨在阐述直立性低血压合并心功能不全时可能的相互作用机制以及此类患者的综合管理的进展,为临床管理提供参考。
英文摘要:
      Orthostatic hypotension is highly prevalent among older adults.The primary pathogenesis includes decreased baroreflex sensitivity,autonomic dysfunction,and hemodynamic abnormalities that lead to impaired blood pressure regulation.It is an important risk factor for cardiovascular and cerebrovascular events,such as acute coronary events,heart failure,and stroke.The comorbidity of heart failure and orthostatic hypotension is common in older adults and is associated with a poor prognosis.In recent years,these patients have gradually received more clinical attention.However,the interaction mechanisms between the two conditions have not been fully elucidated,and literature on the comprehensive management of such patients is limited.This review aims to elucidate the progress of the interaction mechanisms between orthostatic hypotension and heart failure,as well as the comprehensive management of these patients.
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