| 梁睿瑞,刘丹丹,李远远,等.住院老年肌少症患者骨质疏松相关风险及抗阻训练作用的研究[J].中国临床保健杂志,2026,29(2):254-257. |
| 住院老年肌少症患者骨质疏松相关风险及抗阻训练作用的研究 |
| Study on osteoporosis-related risks and the effect of resistance training in elderly inpatients with sarcopenia |
| 投稿时间：2025-06-10 |
| DOI：10.3969/J.issn.1672-6790.2026.02.021 |
| 中文关键词: 肌减少症 骨质疏松 意外跌倒 抗阻训练 老年人 |
| 英文关键词: Sarcopenia Osteoporosis Accidental falls Resistance training Aged 〖FL |
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| 中文摘要: |
| 目的 探究老年肌少症患者中骨质疏松发生率及跌倒和骨折发生的风险,并评估抗阻训练对改善肌少症和骨质疏松症状的潜在效果。方法 前瞻性对照研究。选取2022年8月至2023年7月合肥市第二人民医院老年医学科收治的住院患者124例,其中男53例,女71例。采用双能X线骨密度检测仪对患者的骨量和四肢肌肉含量进行检测,依据肌少症诊断标准分为非肌少症组和肌少症组,并对患者的临床资料及实验室指标进行收集；使用Morse跌倒评估量表对患者跌倒风险进行评估；使用FRAX工具对患者发生骨折的风险进行预测；通过采用双能X射线骨密度检测仪对经过6个月抗阻训练人员的骨骼肌指数和骨密度进行检测。结果 非肌少症组与肌少症组比较,患者性别、体重指数、空腹血糖、三酰甘油、总胆固醇、肌酐和白蛋白等指标差异均无统计学意义,而肌少症组患者年龄高于非肌少症组(P<0.05)；与非肌少症组比较,肌少症组患者骨密度降低或骨质疏松的发生率更高,跌倒风险及未来十年发生骨折的风险也显著增加(P<0.05)；在经过6个月的抗阻训练后,训练组患者的骨骼肌指数及骨密度均有显著的升高(P<0.001)。结论 老年肌少症患者患骨密度降低或骨质疏松的发生率增加,跌倒及骨折的风险显著升高；抗阻训练可显著改善患者的肌少症及骨质疏松。 |
| 英文摘要: |
| Objective To explore the incidence of osteoporosis and the risks of falls and fractures in elderly patients with sarcopenia,and assesse the potential effects of resistance training on improving symptoms of sarcopenia and osteoporosis.Methods Prospective controlled study.A total of 124 hospitalized patients from the geriatrics department of the Second People′s Hospital of Hefei between August 2022 and July 2023 were selected,including 53 male patients and 71 female patients.Bone mineral density and limb muscle content were measured using a dual-energy X-ray absorptiometry scanner.According to diagnostic criteria,patients were divided into a non-sarcopenia group and a sarcopenia group,and their general clinical data and laboratory indicators were assessed.The Morse Fall Scale was used to evaluate the fall risk of the patients,and the FRAX tool was employed to predict the risk of fractures.Using a dual-energy X-ray bone density detector to assess the skeletal muscle index and bone mineral density of individuals who underwent 6 months of resistance training.Results In the comparison between the non-sarcopenia group and the sarcopenia group,there were no statistically significant differences in indicators such as patient gender,BMI,fasting blood glucose,triglycerides,total cholesterol,creatinine,and albumin.However,the age of patients in the sarcopenia group was significantly higher than that in the non-sarcopenia group (P<0.05);compared to the non-sarcopenia group,the sarcopenia group had a higher incidence of reduced bone density or osteoporosis,and the risk of falls as well as the risk of fractures occurring in the next ten years was also significantly increased (P<0.05);after 6 months of resistance training,the skeletal muscle index and bone mineral density of the training group showed a significant increase compared to the control group (P<0.001).Conclusions Patients with sarcopenia in old age have an increased incidence of decreased bone density or osteoporosis,significantly raising the risk of falls and fractures;resistance training can significantly improve the symptoms of sarcopenia and osteoporosis. |
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