文章摘要
陆华东,冯学仁,华锋,钟紫外,邱国琴,崔恩海.中重度阻塞性睡眠呼吸暂停低通气综合征患者经鼻持续气道正压通气治疗后近期生活质量研究[J].中国临床保健杂志,2016,(4):349-351.
中重度阻塞性睡眠呼吸暂停低通气综合征患者经鼻持续气道正压通气治疗后近期生活质量研究
Study on short-term quality of life of nasal continuous positive airway pressure treatment for patients with morderate or severe obstructive sleep apnea hypopnea syndrome
投稿时间:2015-06-11  
DOI:10.3969/J.issn.1672-6790.2016.04.004
中文关键词: 睡眠呼吸暂停,阻塞性  连续气道正压通气  睡眠障碍  生活质量
英文关键词: Sleep apnea,obstructive  Continuous positive airway pressure  Sleep disorders  Quality of life〖FL
基金项目:2014年浙江省卫生厅平台计划(骨干人才)项目资助(2014RCA029)
作者单位E-mail
陆华东 浙江大学湖州医院呼吸内科,湖州 313000 wzmc.2006@163.com 
冯学仁 浙江大学湖州医院呼吸内科,湖州 313000  
华锋 浙江大学湖州医院呼吸内科,湖州 313000  
钟紫外 浙江大学湖州医院呼吸内科,湖州 313000  
邱国琴 浙江大学湖州医院呼吸内科,湖州 313000  
崔恩海 浙江大学湖州医院呼吸内科,湖州 313000  
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中文摘要:
      目的 分析经鼻持续气道正压通气(nCPAP)对阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者近期睡眠疗效、生活质量的影响。方法 选择100例中、重度OSAHS患者作为研究对象,根据治疗情况分为nCPAP组(n=60)和未治疗组(n=40),同时选择同期本院门诊健康体检者20例作为对照组,比较nCPAP组、未治疗组的多导睡眠图(PSG)监测结果、魁北克睡眠问卷(QSQ)评分。结果 治疗后4周,nCPAP组呼吸暂停通气指数(AHI)、最低血氧饱和度、3+4期睡眠比例、快速动眼睡眠比例均优于治疗前及未治疗组(P<0.05);治疗后nCPAP组QSQ各维度评分及总分均高于治疗前及未治疗组(P<0.05),低于对照组(P<0.05)。结论 nCPAP是治疗中、重度OSAHS的有效手段,可以显著改善患者的近期睡眠和生活质量。
英文摘要:
      Objective To investigate the effect of nasal continuous positive airway pressure (nCPAP) on the quality of life and sleep quality for patients with moderate or severe obstructive sleep apnea hypopnea syndrome (OSAHS).Methods 100 patients with moderate or severe OSAHS in our hospital from Ocotober 2014 to March 2015 were selected and divided into nCPAP group (n=60) and untreated group (n=20) according to the treatment 20 healthy cases were collected as control group. The polysomnography (PSG) test results,Quebec sleep questionnaire (QSQ) score,and PSG were compared between the groups.ResultsAfter treatment,the apnea hypopnea index (AHI),the lowest oxygen saturation,the ratio of 3+4 phase of sleep,REM sleep ratio of nCPAP group improved in treatment group (P<0.05).The QSQ score were higher in group nCPAP than before treatment and those in non treatment group (P<0.05),which was lower than that in the control group (P<0.05).ConclusionnCPAP treatment is effective for the patients with OSAHS,which could improve the short-term quality of life.
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