| 金雪华,孟祥博,朱宇婷,张叶芳,卢文杰,方晓芬.药学服务对老年肿瘤患者静脉化疗用药不良反应的影响[J].中国临床保健杂志,2018,21(3):328-330. |
| 药学服务对老年肿瘤患者静脉化疗用药不良反应的影响 |
| Common adverse reactions and pharmaceutical care for intravenous chemotherapy in elderly patients with cancer |
| 投稿时间：2018-01-14 |
| DOI：10.3969/J.issn.1672-6790.2018.03.011 |
| 中文关键词: 药学服务 注射,静脉内 肿瘤 药物疗法 药物毒性 老年人 |
| 英文关键词: Pharmaceutical services Injections,intravenous Neoplasms Drug therapy Drug toxicity Aged〖FL |
| 基金项目:浙江省中医药科学研究基金项目(2015ZA132) |
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| 中文摘要: |
| 目的 分析老年肿瘤患者静脉化疗用药常见的不良反应,并探讨药学服务对其影响。方法 选取90例接受静脉化疗的老年患者,采用随机数字表法将其分为两组。对照组45例予以常规干预,研究组45例在常规干预的同时予以药学服务。观察两组不良反应发生情况与患者生活质量。结果 研究组血液系统、消化系统、皮肤及其附件不良反应发生率均低于对照组。且研究组重度不良反应发生率为11.1%,低于对照组的33.3%,差异有统计学意义(P＜0.05)。干预后研究组整体健康、功能领域评分显著较对照组高,症状领域评分明显低于对照组,差异均有统计学意义(P＜0.05)。结论 为接受静脉化疗的老年肿瘤患者提供药学服务可使不良反应减少,有利于提升生活质量。 |
| 英文摘要: |
| Objective To analyze the common adverse reactions of intravenous chemotherapy in elderly patients with tumor and summarize the pharmaceutical care measures.Methods 90 cases of elderly cancer patients receiving intravenous chemotherapy were randomly divided into two groups.Among them,45 cases in the control group were given routine intervention and other 45 cases in study group were given conventional intervention and our pharmaceutical care.The incidence of adverse reactions and quality of life in the two groups were observed.Results The adverse reaction rates of blood system,digestive system,skin and its accessories in the study group were lower than those in the control group,Moreover,the severe adverse reaction rate was 11.1% in the study group,also lower than 33.3% in the control group,and the difference was statistically significant (P<0.05).After the intervention of pharmaceutical care,the scores of overall health and functional areas were higher and symptom score was significantly lower in the study group than the control group,and the differences were statistically significant (P<0.05).Conclusion The pharmaceutical care for elderly cancer patients receiving intravenous chemotherapy can reduce adverse reactions and improve their quality of life. |
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