| 杨光,赵佳慧,程庆砾.老年肾病综合征的特点与诊治[J].中国临床保健杂志,2020,23(1):30-34. |
| 老年肾病综合征的特点与诊治 |
| Characteristics and diagnosis of nephrotic syndrome in the elderly |
| 投稿时间：2019-12-16 |
| DOI：10.3969/J.issn.1672-6790.2020.01.008 |
| 中文关键词: 肾病综合征 老年人 体征与症状 诊断 |
| 英文关键词: Nephrotic syndrome Aged Pathological conditions,signs and symptoms Diagnosis |
| 基金项目:中国人民解放军总医院第二医学中心保健项目 |
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| 中文摘要: |
| 肾病综合征(NS)是一组以大量蛋白尿、低蛋白血症、高脂血症及水肿为主要特征的临床综合征。包括原发性和继发性两大类。老年NS临床症状常不典型,疾病谱与年轻人不同,继发性NS发病率高,诊断过程中首先应排查继发性因素。继发性因素中以糖尿病肾病、淀粉样变性、肿瘤相关性NS最多见,原发性因素中膜性肾病最常见。此外老年NS患者的感染、血栓、急性肾损伤等并发症发病率高,治疗难度大,临床缓解时间长,激素及免疫抑制剂的应用需根据病情全面权衡利弊,制定个体化的诊疗方案。 |
| 英文摘要: |
| Nephrotic syndrome(NS) is a group of clinical syndromes characterized by massive proteinuria,hypoproteinemia,hyperlipidemia and edema,including primary and secondary two categories.Clinical symptoms of the elderly with NS are often atypical,disease spectrum and young people are different,the incidence of secondary NS is high,the diagnosis process should be the first screening secondary factors.Among the secondary factors,diabetic nephropathy and amyloidosis tumor associated NS were the most common,while primary factors with membranous nephropathy were the most common.In addition,the incidence of complications such as infection,thrombus and acute kidney injury in elderly NS patients with NS is high,the treatment is difficult,and the clinical remission time is long.The application of hormones and immunosuppressants should be based on the comprehensive weighing of the advantages and disadvantages of the disease,and individualized diagnosis and treatment plans should be formulated. |
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