| 曾学寨,刘德平,王丽娟,徐筑津,张晏,王华,张瑞生,周济红,潘春宇,甘宇,乔巍巍.中心动脉血压变异性与高血压左心房扩大的关系[J].中国临床保健杂志,2020,23(1):45-50. |
| 中心动脉血压变异性与高血压左心房扩大的关系 |
| Central blood pressure variability is increased in hypertensive patients with enlarged left atrium |
| 投稿时间：2019-10-31 |
| DOI：10.3969/J.issn.1672-6790.2020.01.011 |
| 中文关键词: 原发性高血压 左心房 动脉压 超声心动描记术 |
| 英文关键词: Essential hypertension Left atrium Arterial pressure Echocardiography |
| 基金项目:国家自然科学基金(51672030) |
| 作者 | 单位 | E-mail | | 曾学寨 | 北京医院心内科,北京 100730 | zxz0588@sina.com | | 刘德平 | 北京医院心内科,北京 100730 | lliudeping@263.net | | 王丽娟 | 北京医院营养科,北京 100730 | | | 徐筑津 | 北京医院放射科,北京 100730 | | | 张晏 | 北京医院特需病房 国家老年医学中心 中国医学科学院老年医学研究院,北京 100730 | | | 王华 | 北京医院心内科,北京 100730 | | | 张瑞生 | 北京医院心内科,北京 100730 | | | 周济红 | 北京医院心内科,北京 100730 | | | 潘春宇 | 北京医院心内科,北京 100730 | | | 甘宇 | 北京医院心内科,北京 100730 | | | 乔巍巍 | 北京医院心内科,北京 100730 | |
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| 中文摘要: |
| 目的 探讨中心动脉血压变异性与高血压左心房扩大的关系。方法 入选原发性高血压136患者,行24 h动态血压监测(采用Mobil-O-Graph NG动态血压监测仪测量中心动脉及肱动脉血压变异性)和超声心动图检查。结果 高血压左心房扩大患者46例(33.8%),与左心房正常的高血压患者相比,左心房扩大高血压患者脉压增大；24 h肱动脉收缩压标准差、24 h中心动脉收缩压标准差增大。经血压校正后回归分析显示24 h中心动脉收缩压标准差与高血压左心房扩大相关,而24 h肱动脉收缩压标准差未达显著性。结论 左心房扩大的高血压患者肱动脉、中心动脉收缩压变异性增高,中心动脉收缩压变异性可能与左心房扩大相关。 |
| 英文摘要: |
| Objective To explore the relationship between central blood pressure variability and left atrial enlargement in patients with hypertension.Methods The blood pressure variability of central artery and brachial artery was measured by Mobil-O-Graph NG ambulatory blood pressure monitor.136 patients with essential hypertension,aged (55±14) years,72% men were studied.Results 46 patients had left atrial enlargement (33.8%).Compared with the patients with normal left atrium,the pulse pressure of patients with left atrium enlargement increased significantly; the 24 h standard deviation of brachial systolic pressure and central systolic pressure increased significantly.Regression analysis after blood pressure correction showed that the standard deviation of 24 h central systolic pressure was significantly correlated with left atrial enlargement in hypertension,while the standard deviation of 24 h brachial systolic pressure was not significant.Conclusion Systolic blood pressure variability of brachial artery and central artery is increased in hypertensive patients with left atrial enlargement,and systolic blood pressure variability of central artery may be correlated with left atrial hypertrophy. |
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