| 詹莹莹,陈锐,杨龙,毛一歆,张羽萍,葛健康.老年综合评估对慢性心力衰竭患者心功能及心血管事件发生的影响[J].中国临床保健杂志,2023,26(2):221-225. |
| 老年综合评估对慢性心力衰竭患者心功能及心血管事件发生的影响 |
| The effect of comprehensive assessment of the elderly cardiac function and cardiovascular events in patients with chronic heart failure |
| 投稿时间：2023-02-22 |
| DOI：10.3969/J.issn.1672-6790.2023.02.018 |
| 中文关键词: 心力衰竭 健康状况指标 心血管疾病 早期医疗干预 老年人 |
| 英文关键词: Heart failure Health status indicators Cardiovascular diseases Early medical intervention Aged 〖FL |
| 基金项目:上海市徐汇区医学科研重大项目(SHXH201903)；江苏大学临床医学科学发展基金项目(JLY20180130) |
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| 中文摘要: |
| 目的 探讨老年综合评估(CGA)指导下的综合干预对慢性心力衰竭患者心功能及不良心血管事件发生率的影响。方法 选取2019年9月至2021年9月上海市第八人民医院收治的年龄≥65岁慢性心力衰竭患者180例,按照随机数字表法分为常规组(90例)、CGA干预组(90例)。干预组在常规药物治疗的前提下,根据CGA结果进行针对性综合干预,包括躯体功能训练、多重用药干预、营养状态管理等。比较2组患者治疗6个月后血浆脑利钠肽、N端脑钠肽前体水平、6 min步行距离及超声心动图结果。比较2组干预后不良心血管事件发生情况。结果 干预组治疗6个月后的左心室射血分数、心排血量、6 min步行距离较前上升(P<0.05)。与常规组相比,干预组脑利钠肽(BNP)水平下降,差异有统计学意义(P<0.05)。CGA干预组心脏不良事件发生率为10.0%,低于常规组的18.9%(P＜0.05)。结论 对于慢性心力衰竭患者通过CGA评估并在其指导下进行有效综合干预措施能够改善患者的心功能,减少不良心血管事件发生。 |
| 英文摘要: |
| Objective To explore the improvement of cardiac function and cardiovascular incidence in patients with chronic heart failure under the guidance of comprehensive geriatric assessment (CGA).Methods One hundred and eighty patients with chronic heart failure aged ≥ 65 years who were admitted to Shanghai Eighth People′s Hospital from September 2019 to September 2021 were randomly divided into routine group (90 cases) and CGA intervention group (90 cases).The intervention group conducted targeted comprehensive intervention according to CGA results under the premise of conventional drug treatment,including physical function training,multi-drug intervention,nutritional status management.Compare the plasma BNP,NT-proBNP,6-min walking distance and echocardiography results of the two groups after 6 months treatment.Compare the occurrence of adverse cardiovascular events between two groups.Results Compared with the control group,after 6 months of treatment in the observation group left ventricular ejection fraction,cardiac output,the 6-min walking distance increased and the BNP level decreased.The difference between the two groups were statistically significant (P<0.05).The incidence of adverse cardiac events in the CGA intervention group was 10.0%,which was lower than the 18.9% in the routine group (P<0.05).Conclusions For patients with chronic heart failure,CGA assessment and interventions can improve the heart function and reduce the occurrence of adverse cardiovascular events of patients. |
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