| 孔祥勇,余小华,匡涛,梁超睿,夏敏文,姚彦鹏,白玛康珠,毛启兄,马礼坤.高原地区非瓣膜性心房颤动与血尿酸水平的相关性研究[J].中国临床保健杂志,2023,26(5):695-698. |
| 高原地区非瓣膜性心房颤动与血尿酸水平的相关性研究 |
| The association between hyperuricemia and atrial fibrillation in general population of the plateau area |
| 投稿时间：2023-08-05 |
| DOI：10.3969/J.issn.1672-6790.2023.05.026 |
| 中文关键词: 心房颤动 高尿酸血症 尿酸 高海拔 危险因素 |
| 英文关键词: Atrial fibrillation Hyperuricemia Uric acid Altitude Risk factors 〖FL |
| 基金项目:西藏自治区自然科学基金项目[XZ2022ZR-ZY35(Z)] |
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| 中文摘要: |
| 目的 探讨高原地区非瓣膜性心房颤动与血尿酸水平之间的相关性。方法 回顾性分析了2021年8月至2022年6月入住山南市人民医院心内科的所有患者病历资料,排除心脏瓣膜病、先天性心脏病患者后最终纳入360例,获得基本数据包括实验室检测、超声心动图、动态心电图和访谈获得的基线特征和一般健康状况。采用logistic回归分析估计尿酸升高和心房颤动患病率之间的关系及不同性别组血尿酸与心房颤动的关系。结果 心房颤动的患病率是17.2%,高尿酸血症组的心房颤动发生率明显高于尿酸正常组(22.4%与10.7%；P=0.004)。在校正混杂变量后,血尿酸与心房颤动的相互关系是独立的(OR=1.003;95%CI:1.000~1.005,P=0.037),尤其是女性(OR=1.004;95%CI:1.001~1.008,P=0.024)。结论 血尿酸与高原地区非瓣膜性心房颤动发生独立相关,尤其是女性。 |
| 英文摘要: |
| Objective To explore the association between atrial fibrillation (AF) and serum uric acid (SUA) in a general population of the plateau area.Methods A retrospective analysis was conducted on the medical records of all patients admitted to the department of cardiology at Shannan People′s Hospital from August 2021 to June 2022.After excluding patients with heart valve disease and congenital heart disease,360 cases were ultimately included.Basic data were obtained from all participants,including baseline characteristics and general health status through laboratory tests,echocardiography,and interviews.Multinomial logistic regression was used to analyze the experimental data and determine the association between SUA and AF.In addition,the relationship between SUA and AF in different gender groups was analyzed.Results The prevalence of AF in this study was 17.2%.Compared with the normal uric acid group,the prevalence of AF in the SUA group was significantly higher (22.4% vs.10.7%;P=0.004).After adjustment for confounding variables,the interrelation of AF on SUA was found to be independent in the total participants (OR=1.003;95%CI:1.000-1.005,P=0.037),especially in women (OR=1.004;95%CI:1.001-1.008,P=0.024).Conclusion SUA is independently associated with AF in general population of the plateau area,especially in women. |
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