| 刘洋,程庆砾.肾脏储备功能最新评估方法简介[J].中国临床保健杂志,2024,(1):47-49. |
| 肾脏储备功能最新评估方法简介 |
| Introduction to the latest evaluation methods for renal reserve function |
| 投稿时间：2023-11-20 |
| DOI：10.3969/J.issn.1672-6790.2024.01.010 |
| 中文关键词: 肾 功能状态 监测,生理学 诊断技术,泌尿科 老年人 |
| 英文关键词: Kidney Functional status Monitoring,physiologic Diagnostic techniques,urological Aged 〖FL |
| 基金项目:中国人民解放军总医院青年自主创新科学基金项目(22QFC007) |
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| 摘要点击次数: 50 |
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| 中文摘要: |
| 肾脏储备功能(RFR)下降可提示亚临床肾功能丧失、慢性肾脏病早期阶段以及患者对急性肾损伤(AKI)易感性。在进行有潜在的肾损害治疗(如手术、化疗等)之前,评估患者对肾脏损害的易感性可能有助于进行个体化治疗和预防AKI。目前常用口服蛋白和静脉输注氨基酸的方法激发并测定RFR,此方法操作复杂、费时且有创,特别是在诊断时间有限,或需要筛查大量人群时更为不便。因此,开发简易、便捷的方法来评估RFR尤为迫切。肾实质内肾抵抗指数变异(IRRIV)与RFR有很好的相关性,应用彩色多普勒超声即可测量IRRIV,是一种安全、可重复、廉价和便捷的测量方法,可用于评估健康受试者的RFR。 |
| 英文摘要: |
| The level of renal functional reserve (RFR) indicates subclinical renal function loss,early stages of chronic kidney disease,and susceptibility to acute kidney injury (AKI).Assessing the patient's susceptibility to kidney damage may help develop personalized treatments and prevent AKI.At present,we commonly give oral protein and intravenous amino acid infusion to stimulate and measure RFR.These methods are complex,time-consuming,and invasive,especially when diagnostic time is limited or a large population needs to be screened.Therefore,developing simple and convenient methods to evaluate RFR is particularly urgent.Recent studies have reported a good correlation between intraparenchymal renal resistance index variation (IRRIV) and RFR.And,the IRRIV can be measured with color Doppler ultrasound.So,this is a safe,repeatable,inexpensive,and convenient method that can be used to evaluate RFR in healthy subjects. |
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