| 朱小川,储德节,曹蕾蕾,沈晔婧,俞静,方子睿.气道正压通气对阻塞性睡眠呼吸暂停低通气综合征合并高血压患者的影响[J].中国临床保健杂志,2024,(1):65-69. |
| 气道正压通气对阻塞性睡眠呼吸暂停低通气综合征合并高血压患者的影响 |
| Impacts of positive airway pressure ventilation on patients with obstructive sleep apnea-hypopnea syndrome combined with hypertension |
| 投稿时间：2023-12-24 |
| DOI：10.3969/J.issn.1672-6790.2024.01.014 |
| 中文关键词: 气道正压通气 阻塞性睡眠呼吸暂停低通气综合征 高血压 认知功能 |
| 英文关键词: Positive airway pressure ventilation Obstructive sleep apnea-hypopnea syndrome Hypertension Cognitive function 〖FL |
| 基金项目:上海市第八人民医院资助项目(SHBY201909) |
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| 中文摘要: |
| 目的 探究气道正压通气对阻塞性睡眠呼吸暂停低通气综合征(OSAHS)合并高血压患者睡眠呼吸暂停低通气指数(AHI)、血压及认知功能的影响。方法 选取2022年3月至2023年1月上海市第八人民医院收治的88例OSAHS合并高血压患者,按照随机数字表法分为干预组(44例)与对照组(44例)。对照组采用常规治疗,干预组在对照组的基础上加用气道正压通气治疗。比较2组患者的睡眠监测结果、血压水平、认知和嗜睡评定及生活质量。结果 治疗后干预组患者的AHI和最长呼吸暂停时间数值均比治疗前降低(P＜0.05),且干预组的数值均较对照组更低(P＜0.05)；治疗后2组24 h平均收缩压、舒张压和夜间收缩压、舒张压均降低,且干预组的血压水平降低幅度较对照组更明显(P＜0.05)；治疗后2组患者的蒙特利尔认知评估量表(MoCA)评分均有提升,Epworth嗜睡量表(ESS)评分均有下降,且干预组患者的MoCA和ESS量表评分升高、下降幅度均超过对照组(P＜0.05)；治疗后2组患者的社会生活、物质生活、生理功能和躯体功能指标均有提升,且干预组各项指标较对照组更高(P＜0.05)。结论 气道正压通气能有效降低OSAHS合并高血压患者的AHI指数,降低患者的血压水平,改善患者的认知功能。 |
| 英文摘要: |
| Objective To investigate the impacts of positive airway pressure ventilation on sleep apnea hypopnea index (AHI),blood pressure,and cognitive function in patients with obstructive sleep apnea hypopnea syndrome (OSAHS) and hypertension.Methods A total of 88 patients with OSAHS and hypertension admitted to Shanghai Eighth People′s Hospital from March 2022 to January 2023 were collected and randomly grouped into an intervention group (44 cases) and a control group (44 cases).The control group received conventional treatment,and the intervention group was treated with positive airway pressure ventilation on the basis of the control group.Sleep monitoring results,blood pressure levels,cognitive and somnolence disorders and quality of life were compared between the two groups.Results After treatment,AHI and longest apnea time in intervention group were lower than before treatment (P<0.05),and the values in intervention group were lower than those in control group (P<0.05).After treatment,the 24 h mean systolic blood pressure,diastolic blood pressure and night systolic and diastolic blood pressure were decreased in both groups,and the reduction of blood pressure level in the intervention group was more obvious (P<0.05).After treatment,the MoCA score of both groups increased,and the ESS score decreased,and the MoCA and ESS scale scores of the intervention group increased and decreased more than those of the control group (P<0.05).After treatment,the indexes of social life,material life,physiological function and physical function of the two groups were improved,and the indexes of the intervention group were significantly higher (P<0.05) than those of control group.Conclusions Positive airway pressure ventilation can effectively reduce the AHI index,blood pressure level,and improve cognitive function in patients with OSAHS and hypertension. |
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