| 戴维德,陈秀华,马娜,等.超声引导细针抽吸细胞块免疫组织化学检查对甲状腺癌的诊断价值[J].中国临床保健杂志,2017,20(3):225-227. |
| 超声引导细针抽吸细胞块免疫组织化学检查对甲状腺癌的诊断价值 |
| The evaluation of ultrasound-guided fine needle aspiration cytology combined with cell block immunohistochemistry in the diagnosis of thyroid carcinoma |
| 投稿时间：2017-01-13 |
| DOI：10.3969/J.issn.1672-6790.2017.03.001 |
| 中文关键词: 甲状腺肿瘤 活组织检查,细针 免疫组织化学 超声检查 |
| 英文关键词: Thyroid neoplasms Biopsy,fine-needle Immunohistochemistry Ultrasonography 〖FL |
| 基金项目:国家科技支撑计划课题(2014BAI08B03) |
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| 中文摘要: |
| 目的 探讨超声引导细针抽吸细胞块免疫组织化学检查对于甲状腺癌的诊断价值。方法 对54例甲状腺结节患者进行超声引导下细针穿刺抽吸,所获得标本送细胞学检查和组织块免疫组织化学检测。将穿刺病理结果与术后病理结果或随访结果进行回顾性分析及对比。结果 穿刺取材成功率为96.3％(52/54)。52例患者中,47例细胞学检查与细胞块免疫组织化学检测联合诊断结果与随访结果相符,临床诊断符合率为90.4%(47/52)。细胞块免疫组织化学检测结果:甲状腺癌36例,良性病变11例。术后病理或临床随访结果:甲状腺癌39例,良性病变13例。该技术对甲状腺癌的诊断敏感度为92.3%(36/39),特异度为100%(11/11)。结论 超声引导细针抽吸细胞块免疫组织化学检测技术对甲状腺癌的诊断简便实用、安全可靠、准确率高。 |
| 英文摘要: |
| Objective To evaluate the clinical value of ultrasound-guided fine needle aspiration cytology combined with cell block immunohistochemistry in diagnosing thyroid carcinoma.Methods Thyroid nodules of 54 patients were punctured and aspirated by using fine needle under ultrasound-guided.The obtained samples were tested for cytology and cell block was detected by immunohistochemistry.The conclusions and the follow-up results were retrospectively analyzed and compared.Results The puncture success rate of this group was 96.3％(52/54).Among 52 patients,the results of the cytology combined with cell block immunohistochemistry of 47 cases were consistent with follow-up results.The coincidence rate of clinical diagnosis was 90.4%(47/52).The diagnose results of cytology combined with cell block immunohistochemistry:36 cases of thyroid carcinoma,11 cases of benign lesion.The pathology diagnoses results after operation or follow-up:39 cases of thyroid carcinoma,13 cases of benign lesion.The sensitivity and specificity of diagnose was 92.3%(36/39) and 100%(11/11),respectively.Conclusion Ultrasound-guided fine needle aspiration cytology combined with cell block immunohistochemical diagnosis of thyroid carcinoma is simple,practical,safe and reliable. |
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