| 张守字.血管性认知障碍的诊断与治疗[J].中国临床保健杂志,2020,23(2):161-164. |
| 血管性认知障碍的诊断与治疗 |
| Diagnosis and treatment of vascular cognitive impairment |
| 投稿时间：2019-09-22 |
| DOI：10.3969/J.issn.1672-6790.2020.02.005 |
| 中文关键词: 痴呆,血管性 诊断技术,神经病学 药物疗法 综述 |
| 英文关键词: Dementia,vascular Diagnostic Techniques,Neurological Drug therapy Review 〖FL |
| 基金项目: |
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| 中文摘要: |
| 血管性认知障碍(VCI)是继阿尔茨海默病(AD)之后第2个常见的痴呆病因。临床发病可以是急性起病,有明确的卒中病史；也可以是渐进或隐袭起病,通常没有明显的卒中病史,经历轻度认知损害(MCI)逐渐发展为痴呆,临床主要依据患者发病特征和认知功能下降表现,结合影像学特征进行诊断。循证医学证据证明,胆碱酯酶抑制剂及兴奋性氨基酸(NMDA)受体拮抗剂对血管性认知障碍治疗有一定疗效。 |
| 英文摘要: |
| Cognitive impairment of vascular (VCI) is one of the most common cause of clinically diagnosed dementia,which is the second after Alzheimer′s disease.The processing of VCI may be acute with a clear history of stroke.The processing of VCI may be gradual or insidious without a clear history of stroke,gradually developing into dementia from mild cognitive impairment (MCI).Clinical diagnosis would mainly base on the patient′s characteristics and cognitive decline performance combined with brain imaging.Evidence-based medical evidence shows that cholinesterase inhibitors and NMDA receptor antagonists have certain therapeutic effects on vascular cognitive impairment. |
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