| 李娟,朱向荣,章霓,冯惠春,胡波,石蕾.肠内营养对晚期胃癌化疗患者营养指标的影响[J].中国临床保健杂志,2023,26(2):230-232. |
| 肠内营养对晚期胃癌化疗患者营养指标的影响 |
| Effect of enteral nutrition on nutritional indexes in patients with advanced gastric cancer undergoing chemotherapy |
| 投稿时间：2022-10-16 |
| DOI：10.3969/J.issn.1672-6790.2023.02.020 |
| 中文关键词: 胃肿瘤 药物疗法 营养支持 生活质量 体重与身体测量 |
| 英文关键词: Stomach neoplasms Drug therapy Nutritional support Quality of life Body weights and measures 〖FL |
| 基金项目:浙江省杭州市卫生科技计划一般项目(A20200746) |
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| 中文摘要: |
| 目的 研究肠内营养对晚期胃癌化疗患者营养指标的影响。方法 选取2020年1月至2022年1月40例晚期胃癌化疗患者作为研究对象,采用随机数字表法分为对照组(20例)与研究组(20例)。给予对照组患者常规化疗方案治疗,研究组患者在对照组的基础上联合肠内营养治疗,2组患者均连续治疗42 d。比较2组患者治疗前后身体测量指标、生活质量及营养指标情况。结果 与治疗前相比,治疗后研究组患者右上臂周围、左上臂周围、体重指数(BMI)、血红蛋白(Hb)、白蛋白(ALB)、转铁蛋白(TF)、前清蛋白(PA)水平升高,对照组患者右上臂周围、左上臂周围、BMI、血Hb、ALB、TF、PA水平降低,研究组高于对照组；与治疗前相比,治疗后2组患者躯体功能、角色功能、情绪功能、认知功能和社会功能评分降低,其中研究组高于对照组(P值均<0.05)。结论 肠内营养可有效缓解晚期胃癌化疗患者可有效缓解营养不良症状,改善生活质量,优化营养状态指标和提高预后。 |
| 英文摘要: |
| Objective To investigate the effects of enteral nutrition on nutritional indexes in patients with advanced gastric cancer undergoing chemotherapy.Methods A total of 40 patients with advanced gastric cancer receiving chemotherapy from January 2020 to January 2022 were selected as research objects and divided into the control group (20 cases) and the study group (20 cases) by random number table method.The study group was treated with conventional chemotherapy,and the observation group was treated with enteral nutrition on the basis of the control group.Both groups were treated continuously for 42 d.Body measurements,quality of life and nutritional indexes of the two groups were compared before and after treatment.Results Compared with before treatment,the levels of body mass index (BMI),serum hemoglobin (Hb),albumin (ALB),transferrin (TF) and prealbumin (PA),the values around the right upper arm and around the left upper arm in the study group increased after treatment,the levels of BMI,serum Hb,ALB,TF,PA and the values around the right upper arm and around the left upper arm in control group decreased,and the levels in the study group were higher than those in the control group.Compared with before treatment,the scores of physical function,role function,emotional function,cognitive function and social function were lower in the two groups after treatment,and the scores in the study group were higher than those in the control group (all P<0.05).Conclusions Enteral nutrition can effectively relieve the symptoms of malnutrition,improve the quality of life,optimize the nutritional status index and improve the prognosis of patients with advanced gastric cancer treated with chemotherapy. |
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