| 王晓培,吕晶,梁嫦娜,李昭,耿瀛洲,路万虹.腹膜透析患者睡眠障碍的影响因素分析[J].中国临床保健杂志,2023,26(3):327-331. |
| 腹膜透析患者睡眠障碍的影响因素分析 |
| The influencing factors of sleep disorders in peritoneal dialysis patients |
| 投稿时间：2023-02-17 |
| DOI：10.3969/J.issn.1672-6790.2023.03.009 |
| 中文关键词: 腹膜透析 入睡和睡眠障碍 危险因素 营养不良 抑郁 |
| 英文关键词: Peritoneal dialysis Sleep initiation and maintenance disorders Risk factors Malnutrition Depression 〖FL |
| 基金项目:陕西省自然科学基础研究计划项目(2022JM-598) |
|
| 摘要点击次数: 603 |
| 全文下载次数: 1852 |
| 中文摘要: |
| 目的 探讨导致腹膜透析(PD)患者睡眠障碍的可能原因。方法 通过横断面调查单中心、规律随访超过3个月的PD患者透析充分性及其他生化指标,行匹兹堡睡眠问卷(PSQI)及贝克焦虑量表(BAI)及中文版贝克抑郁量表Ⅱ(BDI-Ⅱ-C),中文版四项目瘙痒量表(FIIQ),比较睡眠障碍患者瘙痒、焦虑抑郁及营养状况。结果 共调查178例,睡眠障碍发生率为26.4%,与无睡眠障碍患者比较,睡眠障碍患者透析时间更长(P=0.022),每日透析液交换次数更多(P=0.006),超敏C反应蛋白(hs-CRP)水平较高(P=0.010),血清白蛋白水平更低(P=0.049)。残肾Kt/V较低(P=0.040),腹膜Kt/V较高(P=0.039)。FIIQ瘙痒总分、BAI焦虑评分和BDI抑郁评分明显较高(分别P=0.001、＜0.001、＜0.001),Karnofsky活动指数明显较低(P=0.024)。皮尔森相关分析示:PSQI评分与年龄(r=0.192,P=0.010)、透析时间(r=0.193,P=0.010)、每日透析液交换次数(r=0.255,P=0.001)、超敏C反应蛋白(r=0.202,P=0.008)、FIIQ瘙痒评分(r=0.304,P<0.001)、BAI(r=0.373,P<0.001)及BDI-Ⅱ-C评分(r=0.377,P<0.001)呈正相关,与残肾Kt/V(r=-0.194,P=0.009)、血清白蛋白(r=-0.291,P=0.011)呈负相关；多因素logistic回归模型显示:透析时间(P=0.026)、抑郁评分(P=0.035)和低蛋白血症(P=0.036)是PD患者睡眠障碍的独立危险因素。结论 PD患者睡眠障碍发生率高,常与焦虑抑郁、瘙痒伴发有关。长程透析、抑郁及低蛋白血症是导致PD患者睡眠障碍的危险因素。 |
| 英文摘要: |
| Objective To investigate the sleep quality,psychology and nutritional status in peritoneal dialysis (PD) patients and discuss the influencing factors of sleep disorders in patients undergoing PD.Methods One hundred and seventy-eight PD patients following-up more than 3 months in single center were involved in the cross-sectional study.The marks including dialysis adequacy and some biochemical indicators,Pittsburgh sleep questionnaire (PSQI) and Beckanxiety scale (BAI) and Chinese Beck depression scale Ⅱ (BDI-Ⅱ-C),Chinese FIIQ pruritus questionnaire were collected,compare the sores in patients with and without sleep disorder individuals.Results The incidence of sleep disorders was 26.4%.Compared with no sleep disturbances,significantly longer PD duration (P=0.022),more daily dialysis exchanges (P=0.006),higher hypersensitive C reaction protein (P=0.010),lower serum albumin (P=0.049),lower urine Kt/V (P=0.040) and higher peritoneal Kt/V(P=0.039),lower Karnofsky activity index(P=0.024),higher FIIQ score (P=0.001),Baker anxiety score (P=0.004) and Baker depression score (P=0.002) were observed in PD patients with sleep disorders.There were no difference of Urea,creatinine,serum phosphorus,hemoglobin,blood pressure and total Kt/V in all patients.The positive correlation were observed between PSQI score and age (r=0.192,P=0.010),dialysis duration (r=0.193,P=0.010),daily dialysis exchange (r=0.255,P=0.001),hs-CRP(r=0.202,P=0.008),FIIQ score (r=0.304,P<0.001),BAI (r=0.373,P<0.001),BDI score (r=0.377,P<0.001) and negatively associated with urine Kt/V (r=-0.194,P=0.009),serum albumin (r=-0.291,P=0.011).Multivariate logistic regression model showed that longer dialysis duration (P=0.026),depression (P=0.035),hypoproteinemia (P=0.036) were independent risk factors for sleep disorders in PD patients.Conclusions The incidence of sleep disorders is high in PD patients.Long dialysis duration,depression and hypoproteinemia are risk factors for sleep disorders in PD patients. |
|
查看全文
|
| 关闭 |
|
|
|