| 伏海昕,朱振涛,王洁,刘庆淮,陈乃梅,敬志果,陆琳.全视网膜激光光凝术治疗老年糖尿病视网膜病变的预后及影响因素[J].中国临床保健杂志,2023,26(6):762-765. |
| 全视网膜激光光凝术治疗老年糖尿病视网膜病变的预后及影响因素 |
| Disease progression and its influencing factors during follow-up after panretinal laser photocoagulation for elderly diabetic retinopathy |
| 投稿时间：2023-08-02 |
| DOI：10.3969/J.issn.1672-6790.2023.06.010 |
| 中文关键词: 糖尿病视网膜病变 激光凝固术 预后 危险因素 老年人 |
| 英文关键词: Diabetic retinopathy Laser coagulation Prognosis Risk Factors Aged 〖FL |
| 基金项目: |
|
| 摘要点击次数: 125 |
| 全文下载次数: 161 |
| 中文摘要: |
| 目的 探讨全视网膜激光光凝术(PRP)治疗老年糖尿病视网膜病变(DR)的预后及影响因素。方法 选取2017年3月至2020年3月南京医科大学第一附属医院眼科因DR接受PRP手术的84例老年患者为研究对象。所有患者均术后7 d起接受随访,随访时间点为术后1、3、6、12个月,并在患者入院复查时进行相关指标检查,根据患者PRP术后12个月是否发生病情进展将其分为进展组和未进展组。应用光学相干断层成像(Cirrus HD-OCT))测定黄斑中心凹下脉络膜厚度(SFCT)和黄斑区毛细血管密度(VD)。通过电子病历系统获取并统计所有患者性别、年龄、糖尿病病程、体重指数、合并高血压、合并慢性病、合并高血脂、合并冠心病、DR类型、初诊视力和黄斑水肿程度等临床资料。结果 进展组和未进展组术前、术后1个月SFCT和VD比较,差异无统计学意义(P>0.05),进展组术后6、12个月SFCT和VD水平和未进展组比较,差异有统计学意义(P<0.05)；进展组和未进展组体重指数、合并高血脂、DR类型和黄斑水肿程度比较差异有统计学意义(P<0.05),2组性别、年龄、糖尿病病程、合并高血压、合并慢性肾病、合并冠心病和初诊视力比较,差异无统计学意义(P>0.05)；多因素logistic回归分析结果显示:体重指数、合并高血脂、DR类型和黄斑水肿程度均是导致接受PRP手术老年DR患者随访期间病情进展的独立影响因素(P<0.05)。结论 体重指数、合并高血脂、DR类型和黄斑水肿程度均是导致接受PRP手术老年DR患者随访期间病情进展的独立影响因素,对于存在以上因素患者应加强针对性干预以改善其预后。 |
| 英文摘要: |
| Objective To investigate the disease progression and its influencing factors during follow-up after panretinal laser photocoagulation (PRP) in elderly patients of diabetic retinopathy (DR) of the elderly.Methods Eighty-four elderly patients who underwent PRP surgery for DR at the ophthalmology department of the First Affiliated Hospital of Nanjing Medical University from March 2017 to March 2020 were selected as the research subjects.All patients were followed up 7 days after operation.The follow-up time points were 1,3,6 and 12 months after operation.Whether the patients had disease progression 12 months after PRP surgery were divided into a progression group and a non-progression group.Optical coherence tomography (Cirrus HD-OCT) was used to measure subfoveal choroidal thickness (SFCT) and macular capillary density (VD).Clinical data such as gender,age,duration of diabetes,body mass index,hypertension,chronic disease,hyperlipidemia,coronary heart disease,DR type,newly diagnosed visual acuity and degree of macular edema were obtained and counted through the electronic medical record system.Results There was no significant difference in SFCT and VD between the progression group and the non-progression group before surgery and 1 month after surgery (P>0.05).There was statistically significant difference in SFCT and VD between the progression group and the non-progression group 6 month and 12 month after surgery (P<0.05);the body mass index,the combined hyperlipidemia,the type of DR and the degree of macular edema were significantly different between the progressed group and the non-progressed group (P<0.05).There were no significant differences in gender,age,duration of diabetes,hypertension,chronic kidney disease,coronary heart disease and newly diagnosed visual acuity between the two groups (P>0.05).Blood lipids,DR type and macular edema were all independent influencing factors of disease progression during follow-up in elderly DR patients undergoing PRP surgery (P<0.05).Conlclusions Body mass index,concomitant hyperlipidemia,type of DR and degree of macular edema are all independent influencing factors of disease progression during follow-up in elderly DR patients who underwent PRP surgery.For patients with the above factors,targeted interventions should be strengthened to improve their prognosis. |
|
查看全文
|
| 关闭 |
|
|
|